Cyclic nucleotide-gated cation channel beta-3 is a protein in humans that is encoded by CNGB3 gene. Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
The following Cngb3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Cngb3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF881328MO | Recombinant Mouse Cyclic nucleotide-gated cation channel beta-3 (Cngb3) |
in vitro E.coli expression system |
CSB-YP881328MO1 CSB-EP881328MO1 CSB-BP881328MO1 CSB-MP881328MO1 CSB-EP881328MO1-B |
Recombinant Mouse Cyclic nucleotide-gated cation channel beta-3 (Cngb3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Cngb3 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-CF850746DO | Recombinant Dog Cyclic nucleotide-gated cation channel beta-3 (CNGB3) |
in vitro E.coli expression system |
CSB-YP850746DO1 CSB-EP850746DO1 CSB-BP850746DO1 CSB-MP850746DO1 CSB-EP850746DO1-B |
Recombinant Dog Cyclic nucleotide-gated cation channel beta-3 (CNGB3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Cngb3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP885696HU CSB-EP885696HU CSB-BP885696HU CSB-MP885696HU CSB-EP885696HU-B |
Recombinant Human Cyclic nucleotide-gated cation channel beta-3 (CNGB3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |