DAPK1 (Death Associated Protein Kinase 1) is a Protein Coding gene. Diseases associated with DAPK1 include Pancreatic Ductal Adenocarcinoma and Cervical Squamous Cell Carcinoma. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Autophagy - animal. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein kinase activity. An important paralog of this gene is DAPK3.
Based on more than 13 years of development, CUSABIO has established a mature and efficient system for antibody preparation. The following DAPK1 antibodies are manufactured under the system.
These DAPK1 antibodies are featured with high specificity & sensitivity and wide species reactivity. In order to meet different requirements, CUSABIO is trying to include more antibody types (Monoclonal, Polyclonal, Recombinant, etc) and do more validations so that the researchers can break limits and discover more. In addition, CUSABIO also provides DAPK1 antibody custom service in case you have specific needs for your research.
DAPK1 Antibodies for Homo sapiens (Human)
|Code||Product Name||Species Reactivity||Application|
|CSB-PA007645||Human,Mouse||IHC, IF, ELISA|
|CSB-PA007646||Human,Mouse||WB, IHC, IF, ELISA|
Death-associated protein kinase 1 is a protein in humans that is encoded by the DAPK1 gene. The DAPK1 is a calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. It regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylation of TPM1 by DAPK1 enhances stress fiber formation in endothelial cells.