FTH1 (Ferritin Heavy Chain 1) is one of the main storage proteins for iron in the body. It combines with another protein, FTL (Ferritin Light Chain), to form a complex called ferritin, which serves as an iron carrier. This complex efficiently binds and stores free iron molecules in a non-toxic form within cells. When the body requires iron, FTH1 can release stored iron to be utilized by cells and tissues. This regulation of iron storage and release is crucial for maintaining iron balance and metabolic homeostasis in the body. Research on FTH1 contributes to a better understanding of iron metabolism, cellular stress responses, and other physiological processes, providing a theoretical foundation for the study and treatment of related diseases.
● FTH1 Recombinant Monoclonal Antibody CSB-RA009030MA1HU
Validated Data
Positive WB detected in: U251 whole cell lysate,JK whole cell lysate
All lanes: FTH1 antibody at 1:500
Secondary
Goat polyclonal to mouse IgG at 1/50000 dilution
Predicted band size: 22 kDa
Observed band size: 22 kDa
IHC image of CSB-RA009030MA1HU diluted at 1:50 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.
IHC image of CSB-RA009030MA1HU diluted at 1:50 and staining in paraffin-embedded human rectal cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB
Overlay Peak curve showing 293 cells stained with CSB-RA009030MA1HU (red line) at 1:50. Then 10% normal goat serum was Incubated to block non-specific protein-protein interactions followed by the antibody (1µg/1*106cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed
The following Fth1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Fth1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA02084A0Rb | FTH1 Antibody |
Human | ELISA |
CSB-PA02084B0Rb | FTH1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA02084C0Rb | FTH1 Antibody, FITC conjugated |
Human | |
CSB-PA02084D0Rb | FTH1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA02089A0Rb | FTH1 Antibody |
Human | ELISA |
CSB-PA02089B0Rb | FTH1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA02089D0Rb | FTH1 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA008485 | FTH1 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA358768 | FTH1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA247700 | FTH1 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-RA574579A0HU | FTH1 Recombinant Monoclonal Antibody |
Human, Mouse | ELISA, WB, IF, FC |
CSB-RA009030MA1HU | FTH1 Recombinant Monoclonal Antibody |
Human | ELISA, WB, IHC, FC |
Fth1 Antibodies for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA327818XA01SVG | FTH1 Antibody |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ELISA, WB (ensure identification of antigen) |
Fth1 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP009030PI CSB-EP009030PI CSB-BP009030PI CSB-MP009030PI CSB-EP009030PI-B |
Recombinant Pig Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Ovis aries (Sheep)
Code | Product Name | Source |
---|---|---|
CSB-YP009030SH CSB-EP009030SH CSB-BP009030SH CSB-MP009030SH CSB-EP009030SH-B |
Recombinant Sheep Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Oryctolagus cuniculus (Rabbit)
Code | Product Name | Source |
---|---|---|
CSB-YP009030RB CSB-EP009030RB CSB-BP009030RB CSB-MP009030RB CSB-EP009030RB-B |
Recombinant Rabbit Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP009030HU CSB-EP009030HU CSB-BP009030HU CSB-MP009030HU CSB-EP009030HU-B |
Recombinant Human Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP009030HU1 | Recombinant Human Ferritin heavy chain (FTH1) |
E.coli |
Fth1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP009030MO CSB-EP009030MO CSB-BP009030MO CSB-MP009030MO CSB-EP009030MO-B |
Recombinant Mouse Ferritin heavy chain (Fth1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP009030BO CSB-EP009030BO CSB-BP009030BO CSB-MP009030BO CSB-EP009030BO-B |
Recombinant Bovine Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP009030RA CSB-EP009030RA CSB-BP009030RA CSB-MP009030RA CSB-EP009030RA-B |
Recombinant Rat Ferritin heavy chain (Fth1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Code | Product Name | Source |
---|---|---|
CSB-YP009030DXU CSB-EP009030DXU CSB-BP009030DXU CSB-MP009030DXU CSB-EP009030DXU-B |
Recombinant Cricetulus griseus Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Felis catus (Cat) (Felis silvestris catus)
Code | Product Name | Source |
---|---|---|
CSB-YP646663CA CSB-EP646663CA CSB-BP646663CA CSB-MP646663CA CSB-EP646663CA-B |
Recombinant Cat Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Code | Product Name | Source |
---|---|---|
CSB-YP728971PYX CSB-EP728971PYX CSB-BP728971PYX CSB-MP728971PYX CSB-EP728971PYX-B |
Recombinant Pongo abelii Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-YP842569DO CSB-EP842569DO CSB-BP842569DO CSB-MP842569DO CSB-EP842569DO-B |
Recombinant Dog Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Trichosurus vulpecula (Brush-tailed possum)
Code | Product Name | Source |
---|---|---|
CSB-YP895017TQG CSB-EP895017TQG CSB-BP895017TQG CSB-MP895017TQG CSB-EP895017TQG-B |
Recombinant Trichosurus vulpecula Ferritin heavy chain (FTH1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Code | Product Name | Source |
---|---|---|
CSB-CF327818SVG | Recombinant Saccharomyces cerevisiae Iron transporter FTH1 (FTH1) |
in vitro E.coli expression system |
CSB-YP327818SVG1 CSB-EP327818SVG1 CSB-BP327818SVG1 CSB-MP327818SVG1 CSB-EP327818SVG1-B |
Recombinant Saccharomyces cerevisiae Iron transporter FTH1 (FTH1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Fth1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E16932h | Human Ferritin, Heavy Polypeptide (FTH) ELISA Kit |
serum, plasma, cell culture supernates, tissue homogenates | 0.11 ng/mL |
Fth1 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL009030MO | Mouse Ferritin heavy chain(FTH1) ELISA kit |
serum, plasma, tissue homogenates | 0.078 ng/mL |
Fth1 ELISA Kit for Sus scrofa (Pig)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL009030PI | Pig Ferritin heavy chain(FTH1) ELISA kit |
serum, plasma, tissue homogenates | 1.175 ng/ml |