Gipr

Gastric inhibitory polypeptide receptor is a protein in humans that is encoded by GIPR gene. The gastric inhibitory polypeptide receptor (GIP-R) also known as the glucose-dependent insulinotropic polypeptide receptor is a protein that in humans is encoded by the GIPR gene. The GIP-R is seven-transmembrane proteins found on beta-cells in the pancreas. Gastric inhibitory polypeptide (GIP), also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. It was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP.

More Interesting read related GIPR: the Crucial Regulator of Glucose and Lipid Metabolism in Diabetes and Obesity!

Popular Product

● Recombinant Mouse Gastric inhibitory polypeptide receptor(Gipr),partial (Active) CSB-MP009438MO1

Validated Data

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Gipr at 2μg/mL can bind Anti-Mouse Gipr recombinant antibody (CSB-RA009438MA1MO)， the EC₅₀ is 8.622-11.36 ng/mL.

● Recombinant Rat Gastric inhibitory polypeptide receptor(Gipr),partial (Active) CSB-MP009438RA1

Validated Data

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Rat Gipr at 2μg/mL can bind Anti-Mouse Gipr recombinant antibody (CSB-RA009438MA1MO)， the EC₅₀ is 6.946-8.740 ng/mL.

● Gipr Recombinant Monoclonal Antibody CSB-RA009438MA1MO

Validated Data

Excellent Bioactivity Validated by Functional ELISA

The Binding Activity of Rat Giprwith Anti-Mouse Gipr recombinant antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Rat Gipr (CSB-MP009438RA1) at 2 μg/mL can bind Anti-Mouse Gipr recombinant antibody, the EC₅₀ is 6.946-8.740 ng/mL