[Pyruvate dehydrogenase is a protein in humans that is encoded by PDK1 gene. Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
The following Pdk1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Pdk1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA017727GA01HU | PDK1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA296362 | PDK1 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA003729 | PDK1 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA613584LA01HU | PDK1 Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA613584LB01HU | PDK1 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA613584LC01HU | PDK1 Antibody, FITC conjugated |
Human | |
CSB-PA613584LD01HU | PDK1 Antibody, Biotin conjugated |
Human | ELISA |
Pdk1 Antibodies for Drosophila melanogaster (Fruit fly)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA894764XA01DLU | Pdk1 Antibody |
Drosophila melanogaster (Fruit fly) | ELISA, WB (ensure identification of antigen) |
Pdk1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP613584HU CSB-EP613584HU CSB-BP613584HU CSB-MP613584HU CSB-EP613584HU-B |
Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Pdk1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP730872RA CSB-EP730872RA CSB-BP730872RA CSB-MP730872RA CSB-EP730872RA-B |
Recombinant Rat [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (Pdk1) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Pdk1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP807321MO CSB-EP807321MO CSB-MP807321MO CSB-EP807321MO-B |
Recombinant Mouse [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (Pdk1) |
Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
CSB-BP807321MO | Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Pdk1) |
Baculovirus |
Pdk1 Proteins for Drosophila melanogaster (Fruit fly)
Code | Product Name | Source |
---|---|---|
CSB-YP894764DLU CSB-EP894764DLU CSB-BP894764DLU CSB-MP894764DLU CSB-EP894764DLU-B |
Recombinant Drosophila melanogaster 3-phosphoinositide-dependent protein kinase 1 (Pdk1), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |