TNF Proteins

TNF (Tumor Necrosis Factor) is a Protein Coding gene. Diseases associated with TNF include Asthma and Malaria. Among its related pathways are MicroRNAs in cardiomyocyte hypertrophy and Amyotrophic lateral sclerosis (ALS). Gene Ontology (GO) annotations related to this gene include identical protein binding and cytokine activity. An important paralog of this gene is LTA.

CUSABIO supplies a wide range of high-quality recombinant proteins supported by extensive research, development, and validation. We have five recombinant expression systems including Yeast, E. coli, Baculovirus-infected insect cell, Mammalian cell and Cell-free (in vitro E.coli). Our recombinant proteins are featured with high purity and low endotoxin. A part of them has been validated for activity. Anyway, the quality can be guaranteed.
The TNF proteins in the following catalog have all features mentioned above. And you will have many options on sizes from sample sizes to bulk ones. Moreover, TNF proteins custom service is also available for researchers who have more needs for the experiments.

TNF Proteins Catalog

TNF Proteins for Bos taurus (Bovine)

TNF Proteins for Ovis aries (Sheep)

TNF Proteins for Cavia porcellus (Guinea pig)

TNF Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

TNF Proteins for Mus musculus (Mouse)

TNF Proteins for Trichosurus vulpecula (Brush-tailed possum)

TNF Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

TNF Proteins for Rattus norvegicus (Rat)

TNF Proteins for Papio sp. (Baboon)

TNF Proteins for Peromyscus leucopus (White-footed mouse)

TNF Proteins for Cervus elaphus (Red deer)

TNF Proteins for Bos indicus (Zebu)

TNF Proteins for Bubalus bubalis (Domestic water buffalo)

TNF Proteins for Lama glama (Llama)

TNF Proteins for Papio anubis (Olive baboon)

TNF Proteins for Marmota monax (Woodchuck)

TNF Proteins for Papio hamadryas ursinus (Chacma baboon)

TNF Proteins for Macropus eugenii (Tammar wallaby) (Notamacropus eugenii)

TNF Proteins for Callithrix jacchus (White-tufted-ear marmoset)

TNF Proteins for Boselaphus tragocamelus (Nilgai)

TNF Proteins for Dasypus novemcinctus (Nine-banded armadillo)

TNF Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

TNF Proteins for Tupaia tana (Large tree shrew)

TNF Proteins for Camelus bactrianus (Bactrian camel)

TNF Proteins for Pan troglodytes (Chimpanzee)

TNF Proteins for Sparus aurata (Gilthead sea bream)

TNF Proteins for Saimiri sciureus (Common squirrel monkey)

TNF Proteins for Delphinapterus leucas (Beluga whale)

TNF Proteins for Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)

TNF Proteins for Homo sapiens (Human)

TNF Proteins for Macaca mulatta (Rhesus macaque)

TNF Proteins for Sus scrofa (Pig)

TNF Proteins for Felis catus (Cat) (Felis silvestris catus)

TNF Proteins for Capra hircus (Goat)

TNF Proteins for Equus caballus (Horse)

TNF Proteins for Oryctolagus cuniculus (Rabbit)

TNF Background

Tumor necrosis factor is a protein in humans that is encoded by TNF gene. As a cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions, it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective.


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