Transferrin (TF) is an important β-globulin that primarily functions as a transporter of iron ions in the blood plasma. Its structure consists of a single-chain glycoprotein with a molecular weight of approximately 77,000 and a carbohydrate content of about 6%. This protein exhibits the unique ability to reversibly bind multiple ions, particularly iron ions, with each molecule capable of binding two trivalent iron atoms, thereby facilitating efficient iron ion transport within the body. Functionally, transferrin not only transports iron in the form of the TRF-Fe3+ complex to the bone marrow for the production of mature red blood cells, but also forms stable complexes with iron ions during iron excess, preventing toxic accumulation and oxidative damage. Additionally, it plays a crucial role in regulating the balance of iron ions in the body, ensuring that the iron needs of cells and tissues are met, thus maintaining iron homeostasis. Notably, transferrin, through its interaction with transferrin receptor (TfR), has the potential to activate signaling pathways involved in cell proliferation, differentiation, apoptosis, and immune responses, providing a novel targeting agent for tumor cell diagnosis and treatment. However, further research is warranted to fully understand the detailed mechanisms of the transferrin signaling pathway and its role in biological organisms.
Recombinant Human Tissue factor (F3), partial
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP007928HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) F3.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP007928HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) F3.
The following Tf reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Tf Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA00250E0Rb | TF Antibody |
Human | ELISA, WB |
CSB-PA00250F0Rb | TF Antibody, HRP conjugated |
Human | ELISA |
CSB-PA00250G0Rb | TF Antibody, FITC conjugated |
Human | |
CSB-PA00250H0Rb | TF Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA023412GA01HU | TF Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA007928LA01HU | F3 Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
CSB-MA000313 | TF Monoclonal Antibody |
Human | ELISA,WB |
CSB-PA004263 | F3 Antibody |
Human,Monkey | WB, ELISA |
CSB-PA005114 | F3 Antibody |
Human | WB, ELISA |
CSB-PA005189 | TF Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA008166 | Phospho-F3 (S290) Antibody |
Human | WB, IHC, ELISA |
CSB-PA080189 | TF Antibody |
Human,Mouse,Rat | WB, IHC |
CSB-PA040718 | F3 Antibody |
Human | ELISA,WB,IHC |
CSB-PA981490 | F3 Antibody |
Human | ELISA,IHC |
CSB-PA917773 | TF Antibody |
Human | ELISA,WB,IHC |
CSB-PA553268 | TF Antibody |
Human | ELISA,WB |
CSB-RA776663A0HU | F3 Recombinant Monoclonal Antibody |
Human, Rat | ELISA, WB, IHC |
Tf Antibodies for Rattus norvegicus (Rat)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA00470E0Rb | Tf Antibody |
Rat | ELISA, WB |
CSB-PA023412ZA01RA | Tf Antibody |
Rattus norvegicus | ELISA, WB (ensure identification of antigen) |
Tf Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA856363LA01MO | Tf Antibody |
Mouse | ELISA, IHC |
CSB-PA856363LB01MO | Tf Antibody, HRP conjugated |
Mouse | ELISA |
CSB-PA856363LC01MO | Tf Antibody, FITC conjugated |
Mouse | |
CSB-PA856363LD01MO | Tf Antibody, Biotin conjugated |
Mouse | ELISA |
Tf Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP007928HU1 CSB-BP007928HU1 CSB-MP007928HU1 CSB-EP007928HU1-B |
Recombinant Human Tissue factor (F3), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF007928HU | Recombinant Human Tissue factor (F3) |
in vitro E.coli expression system |
CSB-EP007928HU1 | Recombinant Human Tissue factor (F3), partial |
E.coli |
CSB-EP007928HU(F2) | Recombinant Human Tissue factor (F3) |
E.coli |
Tf Proteins for Oryctolagus cuniculus (Rabbit)
Code | Product Name | Source |
---|---|---|
CSB-YP023412RB CSB-EP023412RB CSB-BP023412RB CSB-MP023412RB CSB-EP023412RB-B |
Recombinant Rabbit Serotransferrin (TF), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Equus caballus (Horse)
Code | Product Name | Source |
---|---|---|
CSB-YP023412HO CSB-EP023412HO CSB-BP023412HO CSB-MP023412HO CSB-EP023412HO-B |
Recombinant Horse Serotransferrin (TF), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP023412PI CSB-EP023412PI CSB-BP023412PI CSB-MP023412PI CSB-EP023412PI-B |
Recombinant Pig Serotransferrin (TF), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Oryzias latipes (Japanese rice fish) (Japanese killifish)
Code | Product Name | Source |
---|---|---|
CSB-YP023412OFH CSB-EP023412OFH CSB-BP023412OFH CSB-MP023412OFH CSB-EP023412OFH-B |
Recombinant Oryzias latipes Serotransferrin (tf), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Oncorhynchus kisutch (Coho salmon) (Salmo kisutch)
Code | Product Name | Source |
---|---|---|
CSB-YP023412OBH CSB-EP023412OBH CSB-BP023412OBH CSB-MP023412OBH CSB-EP023412OBH-B |
Recombinant Oncorhynchus kisutch Serotransferrin (tf), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-BP023412RA CSB-MP023412RA CSB-EP023412RA-B |
Recombinant Rat Serotransferrin (Tf) |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP023412RA | Recombinant Rat Serotransferrin (Tf) |
Yeast |
CSB-EP023412RA | Recombinant Rat Serotransferrin (Tf) |
E.coli |
Tf Proteins for Pan troglodytes (Chimpanzee)
Code | Product Name | Source |
---|---|---|
CSB-YP023412EQV CSB-EP023412EQV CSB-BP023412EQV CSB-MP023412EQV CSB-EP023412EQV-B |
Recombinant Pan troglodytes Serotransferrin (TF), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Paralichthys olivaceus (Bastard halibut) (Hippoglossus olivaceus)
Code | Product Name | Source |
---|---|---|
CSB-YP023412ERT CSB-EP023412ERT CSB-BP023412ERT CSB-MP023412ERT CSB-EP023412ERT-B |
Recombinant Paralichthys olivaceus Serotransferrin (tf), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP640906BO CSB-EP640906BO CSB-BP640906BO CSB-MP640906BO CSB-EP640906BO-B |
Recombinant Bovine Serotransferrin (TF), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Code | Product Name | Source |
---|---|---|
CSB-YP681367XBF CSB-EP681367XBF CSB-BP681367XBF CSB-MP681367XBF CSB-EP681367XBF-B |
Recombinant Xenopus tropicalis Serotransferrin (tf), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Gadus morhua (Atlantic cod)
Code | Product Name | Source |
---|---|---|
CSB-YP849704GER CSB-EP849704GER CSB-BP849704GER CSB-MP849704GER CSB-EP849704GER-B |
Recombinant Gadus morhua Serotransferrin (tf), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP856363MO CSB-EP856363MO CSB-BP856363MO CSB-MP856363MO CSB-EP856363MO-B |
Recombinant Mouse Serotransferrin (Tf) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tf ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E07913h | Human tissue factor (TF) ELISA kit |
serum, plasma, tissue homogenates | 0.78 pg/mL |
CSB-E13093h | Human transferrin(TF) ELISA Kit |
serum, plasma, urine, cell culture supernates, cerebrospinal fluid (CSF) | 0.006 nmol/L |
Tf ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL023412MO | Mouse Serotransferrin(TF) ELISA kit |
serum, plasma | 3.9 ng/mL |
Tf ELISA Kit for Sus scrofa (Pig)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E13764p | Pig Transferrin(TF) ELISA Kit |
serum, plasma, tissue homogenates | 0.78 μg/mL |
Tf ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E12723r | Rat Transferrin(TF) ELISA Kit |
serum, plasma, tissue homogenates | 1.95 pmol/mL |