osm

OSM (Oncostatin M) is a cytokine protein and a member of the Interleukin-6 (IL-6) family. Its structure consists of a single polypeptide chain that binds to receptors on the cell surface, triggering downstream signal transduction pathways. OSM plays a significant role in immune regulation, cell proliferation, differentiation, and inflammation in various physiological processes. It participates in regulating the proliferation and differentiation of multiple cell types, including hepatocytes, embryonic stem cells, and neurons. In inflammatory diseases, OSM can modulate immune cell activation and inflammatory responses. In tumor development, OSM may contribute to the proliferation and invasion of tumor cells. Given its important role in both physiological and pathological processes, the study of OSM holds crucial implications for understanding immune regulation, inflammatory responses, and tumor biology. Additionally, OSM is considered a potential therapeutic target, and therapeutic approaches targeting OSM and its receptors may aid in modulating disease processes and developing new treatment strategies.

More Interesting read related OSM: Oncostatin M (OSM): A Member of IL-6 Cytokine Family, An Underestimated Player in Future Targeted Therapies?

Popular Product

● OSM Recombinant Monoclonal Antibody CSB-RA017260MA1HU

Validated Data

ELISA

The Binding Activity of Human OSM with Anti-OSM Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM (CSB-MP017260HU1) at 2 μg/mL can bind Anti-OSM recombinant antibody, the EC₅₀ is 3.048-3.860 ng/mL

● Recombinant Human Oncostatin-M(OSM),partial (Active) CSB-MP017260HU1

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM at 2μg/mL can bind Anti-OSM recombinant antibody (CSB-RA017260MA1HU)，the EC₅₀ is 3.048-3.860 ng/mL.