Mothers against decapentaplegic homolog 3 is a protein in humans that is encoded by SMAD3 gene. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive.
The following smad3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
smad3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA021788GA01HU | SMAD3 Antibody |
Human | ELISA,WB,IHC |
CSB-PA021788LA01HU | SMAD3 Antibody |
Human | ELISA, WB |
CSB-PA021788LC01HU | SMAD3 Antibody, FITC conjugated |
Human | |
CSB-PA898915 | Phospho-SMAD3 (Ser425) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA440262 | SMAD3 (Ab-208) Antibody |
Human,Mouse,Rat | ELISA,IHC,IF |
CSB-PA794085 | SMAD3 (Ab-425) Antibody |
Human,Mouse,Rat | ELISA,IHC,IF |
CSB-PA620192 | Phospho-SMAD3 (Ser208) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA909608 | Phospho-SMAD3 (Ser204) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA282191 | Phospho-SMAD3 (Ser213) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA905682 | Phospho-SMAD3 (Thr179) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA103091 | SMAD3 (Ab-204) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA021788ESR2HU | SMAD3 Antibody |
Human | ELISA, WB, IHC, IF, IP |
CSB-PA000651 | Phospho-SMAD3 (S204) Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA000676 | Phospho-SMAD3 (S425) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA000711 | Phospho-SMAD3 (S208) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA004113 | SMAD3 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA004115 | SMAD3 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA009957 | Phospho-SMAD3 (S213) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA009959 | Phospho-SMAD3 (T179) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA009960 | SMAD3 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA080212 | SMAD3 Antibody |
Human,Mouse,Rat | WB, IHC |
CSB-PA080213 | SMAD3 Antibody |
Human | WB, IHC |
CSB-PA039919 | SMAD3 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA033427 | SMAD3 Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-MA388929 | Phospho-SMAD3(S425) Monoclonal Antibody |
Human,Mouse,Rat | ELISA,IHC |
smad3 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA804860XA01MO | Smad3 Antibody |
Mus musculus (Mouse) | ELISA, WB (ensure identification of antigen) |
smad3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP021788HU CSB-MP021788HU CSB-EP021788HU-B |
Recombinant Human Mothers against decapentaplegic homolog 3 (SMAD3) |
Yeast Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP021788HU | Recombinant Human Mothers against decapentaplegic homolog 3 (SMAD3) |
E.coli |
CSB-BP021788HU | Recombinant Human Mothers against decapentaplegic homolog 3 (SMAD3) |
Baculovirus |
smad3 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP021788RA CSB-EP021788RA CSB-BP021788RA CSB-MP021788RA CSB-EP021788RA-B |
Recombinant Rat Mothers against decapentaplegic homolog 3 (Smad3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
smad3 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP021788CH CSB-EP021788CH CSB-BP021788CH CSB-MP021788CH CSB-EP021788CH-B |
Recombinant Chicken Mothers against decapentaplegic homolog 3 (SMAD3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
smad3 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP021788PI CSB-EP021788PI CSB-BP021788PI CSB-MP021788PI CSB-EP021788PI-B |
Recombinant Pig Mothers against decapentaplegic homolog 3 (SMAD3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
smad3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP804860MO CSB-EP804860MO CSB-BP804860MO CSB-MP804860MO CSB-EP804860MO-B |
Recombinant Mouse Mothers against decapentaplegic homolog 3 (Smad3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |