Human Disintegrin and metalloproteinase domain-containing protein 2(ADAM2) ELISA kit

Code CSB-EL001280HU
Size 96T
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Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Target Name
ADAM metallopeptidase domain 2
Alternative Names
A disintegrin and metalloproteinase domain 2 ELISA Kit; ADAM 2 ELISA Kit; ADAM metallopeptidase domain 2 ELISA Kit; Adam2 ELISA Kit; ADAM2_HUMAN ELISA Kit; AI323749 ELISA Kit; Cancer/testis antigen 15 ELISA Kit; CRYN1 ELISA Kit; CRYN2 ELISA Kit; CT15 ELISA Kit; Disintegrin and metalloproteinase domain-containing protein 2 ELISA Kit; Fertilin beta ELISA Kit; Fertilin subunit beta ELISA Kit; Ftnb ELISA Kit; PH 30 ELISA Kit; PH 30b ELISA Kit; PH-30 ELISA Kit; PH30 ELISA Kit; Ph30 beta ELISA Kit; PH30-beta ELISA Kit
Abbreviation
ADAM2
Uniprot No.
Species
Homo sapiens (Human)
Sample Types
serum, plasma, tissue homogenates
Detection Range
0.312 ng/ml - 20 ng/ml
Sensitivity
0.078 ng/ml
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Cancer
Assay Principle
quantitative
Measurement
Sandwich
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx

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Target Background

Function
(From Uniprot)
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
Gene References into Functions
  1. ADAM2, CALR3 and SAGE1 cancer/testis antigens are not promising targets for immunotherapy of breast and lung cancer. PMID: 26252478
  2. The fertilin beta contributes not only to successful fertilization, but may has an important impact in development of preimplantation embryos. PMID: 18292840
Subcellular Location
Membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
Database Links

HGNC: 198

OMIM: 601533

KEGG: hsa:2515

STRING: 9606.ENSP00000265708

UniGene: Hs.177959

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