EphA3-A Regulator of Cell Adhesion and Migration
EphA3-A Regulator of Cell Adhesion and MigrationReceptor tyrosine kinase (RTKs) is a type I transmembrane glycoprotein that regulates cell growth, differentiation and migration. The Eph receptor family (erythropoietin-producing human hepatocellular carcinoma) is the l...
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Ovarian Cancer -- The Silent Killer
Ovarian Cancer -- The Silent KillerThe ovaries are the female reproductive organs that produce eggs. Ovarian cancer refers to the cancerous changes that occur in the ovaries. It is a tumor caused by abnormal, uncontrollable reproduction of certain cells i...
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Growth Hormone - Not Only Promotes Height Increase
Growth Hormone - Not Only Promotes Height IncreaseGrowth hormone 1, also known as somatotropin, or growth hormone (GH). It is a member of the growth hormone/prolactin family. It is a single peptide chain protein hormone secreted by pituitary gland. The role of this horm...
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CD31- A Complex Function Molecule
CD31- A Complex Function MoleculeAt the 2015 ASCO Annual Meeting, the team of Michael J. Birrer, MD, et al. proposed that CD31 is a potential biomarker for bevacizumab in ovarian cancer. Because the effect of bevacizumab on progression-free survival (PF...
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CD14-- A Membrane Receptor for Bacterial Lipopolysaccharides
CD14-- A Membrane Receptor for Bacterial LipopolysaccharidesCD14 (cluster of differentiation 14), formerly known as MY23 antigen, is a surface antigen and is a member of the cell surface glycoprotein family. The protein encoded by the CD14 gene is preferentially expressed in mono...
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Dual Role of TNFRSF14 in Immunology
Dual Role of TNFRSF14 in ImmunologyTumor necrosis factor receptor superfamily member 14 (TNFRSF14) is a member of the TNF receptor superfamily, also known as herpesvirus entry mediator (HVEM), CD270. In addition, it is also known as another TRAF-related r...
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Does TNF Superfamily Inhibit Cancer or Promote Its Development?
Does TNF Superfamily Inhibit Cancer or Promote Its Development?The tumor necrosis factor superfamily (TNFSF) consists of 19 ligands and 29 receptors. TNF superfamily members induce a variety of biological effects, including cell growth, differentiation, and death by the interaction ...
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Tumor Necrosis Factor Receptor Superfamily and Apoptosis
Tumor Necrosis Factor Receptor Superfamily and ApoptosisTumor necrosis factor receptor superfamily (TNFRSF) belongs to the transmembrane protein receptor, and its characteristic structure is its extracellular domain cysteine-rich domain (CRDs), which usually contains 6 cystei...
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IL-6-Do You Really Know That?
IL-6-Do You Really Know That?Interleukin-6, also known as IL-6, is a cytokine that belongs to the class of interleukins. It is produced by fibroblasts, monocytes/macrophages, T lymphocytes, B lymphocytes, epithelial cells, keratinocytes, and various...
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Stem Cell-What a Miraculous Resource in Human Body
Stem Cell-What a Miraculous Resource in Human BodyWhen comes to stem cells, youth and vitality will emerge in our mind. For this reason, stem cells have always been associated with the topic of longevity. But the definition, type and function of stem cells are often ill...
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