CSF2/GM-CSF: A Key Molecule in Immune Regulation and Disease Treatment
CSF2/GM-CSF: A Key Molecule in Immune Regulation and Disease TreatmentIn recent years, CSF2 (Granulocyte-Macrophage Colony-Stimulating Factor, GM-CSF) has garnered significant attention in biomedical research. CSF2 plays a crucial role in immune regulation, inflammatory responses, and tumo...
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The Structure, Function, and Research Progress of Lymphotoxin β Receptor (LTBR) in Disease and Drug Development
The Structure, Function, and Research Progress of Lymphotoxin β Receptor (LTBR) in Disease and Drug DevelopmentLymphotoxin β Receptor (LTBR), also known as Tumor Necrosis Factor Receptor Superfamily Member 3 (TNFRSF3), plays a crucial role in the immune system and is vital for maintaining immune balance and overall health. As re...
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CD79A and CD79B: Key Targets in B Cell Signaling Pathways and Therapeutic Potential
CD79A and CD79B: Key Targets in B Cell Signaling Pathways and Therapeutic PotentialAs crucial components of the B-cell receptor (BCR), CD79A and CD79B play a pivotal role in B-cell signal transduction and have garnered extensive attention in the field of blood cancer treatment. In recent years, signifi...
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TNFSF15/TL1A: The Rise of the Next Billion-Dollar Target as Pharma Giants Stake Their Claims
TNFSF15/TL1A: The Rise of the Next Billion-Dollar Target as Pharma Giants Stake Their ClaimsRecently, there has been a flurry of good news regarding TNFSF15/TL1A. Sansheng Guojian Pharmaceutical(Group)Co., Ltd.'s anti-TL1A monoclonal antibody SSGJ-627 injection has had its IND application accepted by the CD...
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How to Choose An Appropriate Isotype Control Antibody?
How to Choose An Appropriate Isotype Control Antibody?Selecting the appropriate isotype control antibodies is a critical decision in experimental design, yet it often gets considerably less focus than other research components. For many researchers, isotype control is merel...
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Antigen Retrieval: Uncovering Antigen Masking to Improve Immunohistochemistry Results
Antigen Retrieval: Uncovering Antigen Masking to Improve Immunohistochemistry ResultsHave you ever handled fixed tissues? If you prepare tissue sections for immunohistochemistry (IHC), you probably have! In IHC experiments, tissue samples are often treated with chemical fix...
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Advancements in CDH6-Targeted Drug Research for Cancer Treatment
Advancements in CDH6-Targeted Drug Research for Cancer TreatmentRecent advancements in CDH6-targeted drug research include First Three's initiation of the international multicenter Phase II/III clinical trial for its CDH6-targeted antibody-drug conjugate (ADC), R-DXd, marking it as t...
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TIGIT Targeted Immunotherapies Offer New Hope for Cancer Treatment
TIGIT Targeted Immunotherapies Offer New Hope for Cancer TreatmentThe TIGIT target, once hailed as the "next PD-1", has garnered significant attention in the field of immunotherapy. However, its development journey has been fraught with challenges, with numerous pharmaceutical companie...
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How do we dissolve BSA?
How do we dissolve BSA?Bovine Serum Albumin (BSA) is a globulin found in bovine serum, containing 607 amino acid residues, with a molecular weight of 66.446 kDa. It plays significant roles in blood circulation, lipid metabolism, detoxification...
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A Comprehensive Guide to Monoclonal Antibody Production
A Comprehensive Guide to Monoclonal Antibody ProductionMonoclonal antibodies (mAbs) have revolutionized medicine, diagnostics, and research since their discovery. The monoclonal antibody market has seen remarkable growth, estimated to reach over $250 billion globally by 2028...
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