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| Code | CSB-E09299h |
| Size | 96T,5×96T,10×96T |
| See More Details |  |
| Target Name | agouti related protein homolog (mouse) |
| Alternative Names | AGRT, ART, ASIP2, MGC118963, agouti related protein |
| Abbreviation | AGRP |
| Uniprot No. | O00253 |
| Species | Homo sapiens (Human) |
| Sample Types | serum, plasma, cell culture supernates, urine |
| Detection Range | 31.25 pg/mL-2000 pg/mL |
| Sensitivity | 0.002 pg/mL |
| Assay Time | 1-5h |
| Sample Volume | 50-100ul |
| Detection Wavelength | 450 nm |
| Research Area | Cardiovascular |
| Assay Principle | quantitative |
| Measurement | Sandwich |
| Precision | Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess. |
| Linearity | To assess the linearity of the assay, samples were spiked with high concentrations of human AGRP in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. |
| Typical Data | These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. |
| Troubleshooting and FAQs |
ELISA kit FAQs |
| Storage | Store at 2-8°C. Please refer to protocol. |
| Lead Time | 3-5 working days |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. |
| Involvement in disease | Obesity (OBESITY) |
| Subcellular Location | Secreted, Golgi apparatus lumen |
| Tissue Specificity | Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney. |
| Database Links |
HGNC: 330 OMIM: 601665 KEGG: hsa:181 STRING: 9606.ENSP00000290953 UniGene: Hs.104633 |
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