Recombinant Ajellomyces dermatitidis ATPase GET3(GET3)

Product Type Recombinant Protein
Uniprot No. C5JUG0
Species Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis)
Gene Names GET3
Protein Names Recommended name: ATPase GET3 EC= 3.6.-.- Alternative name(s): Arsenical pump-driving ATPase Arsenite-stimulated ATPase Golgi to ER traffic protein 3 Guided entry of tail-anchored proteins 3
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
Subcellular Location Cytoplasm, Endoplasmic reticulum
Protein Families ArsA ATPase family
Database Links

STRING: 559298.XP_002623460.1

Product Details for Different Expression Systems

Product Name Recombinant Ajellomyces dermatitidis ATPase GET3(GET3),Yeast
Code CSB-YP511823AZE
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSSTAIVSGD ESLEPTLQNL LDQKTLRWVF VGGKGGVGKT TTSCSLAIQL AKVRKSVLLI STDPAHNLSD AFGQKFGKEA RLIDGFDNLS AMEIDPNGSI QDLLAAGGDQ ADDPMGGLGL GGMMQDLAFS IPGVDEAMSF AEVLKQVKSL SYEVIIFDTA PTGHTLRFLQ FPTVLEKALG KLSQLSSQFG PMLNSVLGAR GGLPGGQNLD EILSKMESLR ETIGEVNAQF KDADLTTFVC VCIAEFLSLY ETERMIQELT SYQIDTHCIV VNQLLFPGKD SSCEQCKARR KMQKKYLNEI EELYEDFNVV RMPMLVEEVR GKEKLEKFSN MLINPYIPPQ E
Expression Region 1-341
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Ajellomyces dermatitidis ATPase GET3(GET3),E.coli
Code CSB-EP511823AZE
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSSTAIVSGD ESLEPTLQNL LDQKTLRWVF VGGKGGVGKT TTSCSLAIQL AKVRKSVLLI STDPAHNLSD AFGQKFGKEA RLIDGFDNLS AMEIDPNGSI QDLLAAGGDQ ADDPMGGLGL GGMMQDLAFS IPGVDEAMSF AEVLKQVKSL SYEVIIFDTA PTGHTLRFLQ FPTVLEKALG KLSQLSSQFG PMLNSVLGAR GGLPGGQNLD EILSKMESLR ETIGEVNAQF KDADLTTFVC VCIAEFLSLY ETERMIQELT SYQIDTHCIV VNQLLFPGKD SSCEQCKARR KMQKKYLNEI EELYEDFNVV RMPMLVEEVR GKEKLEKFSN MLINPYIPPQ E
Expression Region 1-341
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Ajellomyces dermatitidis ATPase GET3(GET3),Baculovirus
Code CSB-BP511823AZE
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSSTAIVSGD ESLEPTLQNL LDQKTLRWVF VGGKGGVGKT TTSCSLAIQL AKVRKSVLLI STDPAHNLSD AFGQKFGKEA RLIDGFDNLS AMEIDPNGSI QDLLAAGGDQ ADDPMGGLGL GGMMQDLAFS IPGVDEAMSF AEVLKQVKSL SYEVIIFDTA PTGHTLRFLQ FPTVLEKALG KLSQLSSQFG PMLNSVLGAR GGLPGGQNLD EILSKMESLR ETIGEVNAQF KDADLTTFVC VCIAEFLSLY ETERMIQELT SYQIDTHCIV VNQLLFPGKD SSCEQCKARR KMQKKYLNEI EELYEDFNVV RMPMLVEEVR GKEKLEKFSN MLINPYIPPQ E
Expression Region 1-341
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Ajellomyces dermatitidis ATPase GET3(GET3),Mammalian cell
Code CSB-MP511823AZE
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MSSTAIVSGD ESLEPTLQNL LDQKTLRWVF VGGKGGVGKT TTSCSLAIQL AKVRKSVLLI STDPAHNLSD AFGQKFGKEA RLIDGFDNLS AMEIDPNGSI QDLLAAGGDQ ADDPMGGLGL GGMMQDLAFS IPGVDEAMSF AEVLKQVKSL SYEVIIFDTA PTGHTLRFLQ FPTVLEKALG KLSQLSSQFG PMLNSVLGAR GGLPGGQNLD EILSKMESLR ETIGEVNAQF KDADLTTFVC VCIAEFLSLY ETERMIQELT SYQIDTHCIV VNQLLFPGKD SSCEQCKARR KMQKKYLNEI EELYEDFNVV RMPMLVEEVR GKEKLEKFSN MLINPYIPPQ E
Expression Region 1-341
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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