Recombinant Bovine Golgi to ER traffic protein 4 homolog(GET4)

Product Type Recombinant Protein
Uniprot No. Q0P5I8
Abbreviation GET4
Species Bos taurus (Bovine)
Gene Names GET4
Protein Names Recommended name: Golgi to ER traffic protein 4 homolog
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
Subcellular Location Cytoplasm, cytosol
Protein Families GET4 family
Database Links

KEGG: bta:107131133

STRING: 9913.ENSBTAP00000036940

UniGene: Bt.29993

Product Details for Different Expression Systems

Product Name Recombinant Bovine Golgi to ER traffic protein 4 homolog(GET4),Yeast
Code CSB-YP603913BO
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAAAAMAEQE SARNGARNRG GVQRVEGKLR ASVEKGDYYE AHQMYRTLFF RYMAQSKHAE ARELMCSGAL LFFSHGQQNS AADLSMLVLE SLEKAEVEVA DELLESLAKL FSLMDPNSPE RVAFVSRALK WSSGGSGKLG HPRLHQLLAL TLWKEQNYCE SRYHFLHSSD GEGCANMLVE YSTARGFRSE VDMFVAQAVL QFLCLKNKSS ASVVFTTYTQ KHPSIEGGPP FVQPLLNFIW FLLLAVDGGK LTVFTVLCEQ YQPSLRRDPM YNEYLDRIGQ LFFGVPPKQT SSYGGLLGNL LSSLMGSSEQ EGEDSQDDSS PIELD
Expression Region 1-325
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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Product Name Recombinant Bovine Golgi to ER traffic protein 4 homolog(GET4),E.coli
Code CSB-EP603913BO
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAAAAMAEQE SARNGARNRG GVQRVEGKLR ASVEKGDYYE AHQMYRTLFF RYMAQSKHAE ARELMCSGAL LFFSHGQQNS AADLSMLVLE SLEKAEVEVA DELLESLAKL FSLMDPNSPE RVAFVSRALK WSSGGSGKLG HPRLHQLLAL TLWKEQNYCE SRYHFLHSSD GEGCANMLVE YSTARGFRSE VDMFVAQAVL QFLCLKNKSS ASVVFTTYTQ KHPSIEGGPP FVQPLLNFIW FLLLAVDGGK LTVFTVLCEQ YQPSLRRDPM YNEYLDRIGQ LFFGVPPKQT SSYGGLLGNL LSSLMGSSEQ EGEDSQDDSS PIELD
Expression Region 1-325
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Bovine Golgi to ER traffic protein 4 homolog(GET4),Baculovirus
Code CSB-BP603913BO
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAAAAMAEQE SARNGARNRG GVQRVEGKLR ASVEKGDYYE AHQMYRTLFF RYMAQSKHAE ARELMCSGAL LFFSHGQQNS AADLSMLVLE SLEKAEVEVA DELLESLAKL FSLMDPNSPE RVAFVSRALK WSSGGSGKLG HPRLHQLLAL TLWKEQNYCE SRYHFLHSSD GEGCANMLVE YSTARGFRSE VDMFVAQAVL QFLCLKNKSS ASVVFTTYTQ KHPSIEGGPP FVQPLLNFIW FLLLAVDGGK LTVFTVLCEQ YQPSLRRDPM YNEYLDRIGQ LFFGVPPKQT SSYGGLLGNL LSSLMGSSEQ EGEDSQDDSS PIELD
Expression Region 1-325
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Bovine Golgi to ER traffic protein 4 homolog(GET4),Mammalian cell
Code CSB-MP603913BO
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MAAAAMAEQE SARNGARNRG GVQRVEGKLR ASVEKGDYYE AHQMYRTLFF RYMAQSKHAE ARELMCSGAL LFFSHGQQNS AADLSMLVLE SLEKAEVEVA DELLESLAKL FSLMDPNSPE RVAFVSRALK WSSGGSGKLG HPRLHQLLAL TLWKEQNYCE SRYHFLHSSD GEGCANMLVE YSTARGFRSE VDMFVAQAVL QFLCLKNKSS ASVVFTTYTQ KHPSIEGGPP FVQPLLNFIW FLLLAVDGGK LTVFTVLCEQ YQPSLRRDPM YNEYLDRIGQ LFFGVPPKQT SSYGGLLGNL LSSLMGSSEQ EGEDSQDDSS PIELD
Expression Region 1-325
Protein Description full length protein
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Still Have Questions? Leave a Message or Start an on-line Chat

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