Recombinant Human ADAMTS-like protein 3(ADAMTSL3) ,partial

Code CSB-YP001319HU
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Source Yeast
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Code CSB-EP001319HU
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Source E.coli
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Code CSB-EP001319HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP001319HU
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Source Baculovirus
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Code CSB-MP001319HU
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names ADAMTSL3
Uniprot No. P82987
Alternative Names ADAMTSL3; KIAA1233ADAMTS-like protein 3; ADAMTSL-3; Punctin-2
Species Homo sapiens (Human)
Protein Length Partial
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

Target Data

Gene References into Functions
  1. A137T in ADAMTSL3 may be a susceptibility mutation for diabetes. PMID: 29162515
  2. Compared with the George-Abraham' study [2012], ADAMTSL3 might be more related to the cardiac disorders in tetrasomy 15q patients PMID: 24793337
  3. The results of this study suggested that the ADAMTSL3 as a candidate gene for schizophrenia. PMID: 21239144
  4. Highest expression of ADAMTSL3 was found in liver, kidney, heart and skeletal muscle. PMID: 14667842
  5. ADAMTSL3 is expressed in numerous tissues, suggesting a broader regulatory role than in colorectal epithelium alone, and that colorectal cancer has both structural mutations as well as decreased expression of ADAMTSL3. PMID: 17597111

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Subcellular Location Secreted, extracellular space, extracellular matrix
Tissue Specificity Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardia
Database Links

HGNC: 14633

OMIM: 609199

KEGG: hsa:57188

STRING: 9606.ENSP00000286744

UniGene: Hs.459162

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