Recombinant Human Heat shock 70 kDa protein 13 (HSPA13)

Code CSB-YP010819HU
MSDS
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Source Yeast
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Code CSB-EP010819HU
MSDS
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Source E.coli
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Code CSB-EP010819HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP010819HU
MSDS
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Source Baculovirus
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Code CSB-MP010819HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
HSPA13
Uniprot No.
Alternative Names
Heat shock 70 kDa protein 13; HEAT SHOCK 70-KD PROTEIN 13; heat shock protein 70kDa family, member 13; heat shock protein70kDa family, member13; HSP13_HUMAN; HSPA13; MGC133835; Microsomal stress 70 protein ATPase core; Microsomal stress-70 protein ATPase core; STCH; Stress 70 protein chaperone microsome associated 60 kDa protein; Stress-70 protein chaperone microsome-associated 60 kDa protein
Species
Homo sapiens (Human)
Expression Region
23-471
Target Protein Sequence
QQYLPLPT PKVIGIDLGT TYCSVGVFFP GTGKVKVIPD ENGHISIPSM VSFTDNDVYV GYESVELADS NPQNTIYDAK RFIGKIFTAE ELEAEIGRYP FKVLNKNGMV EFSVTSNETI TVSPEYVGSR LLLKLKEMAE AYLGMPVANA VISVPAEFDL KQRNSTIEAA NLAGLKILRV INEPTAAAMA YGLHKADVFH VLVIDLGGGT LDVSLLNKQG GMFLTRAMSG NNKLGGQDFN QRLLQYLYKQ IYQTYGFVPS RKEEIHRLRQ AVEMVKLNLT LHQSAQLSVL LTVEEQDRKE PHSSDTELPK DKLSSADDHR VNSGFGRGLS DKKSGESQVL FETEISRKLF DTLNEDLFQK ILVPIQQVLK EGHLEKTEID EVVLVGGSTR IPRIRQVIQE FFGKDPNTSV DPDLAVVTGV AIQAGIDGGS WPLQVSALEI PNKHLQKTNF N
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Has peptide-independent ATPase activity.
Gene References into Functions
  1. novel role of STCH in the regulation of pHi through site-specific interactions with NBCe1-B and NHE1 and subsequent modulation of membrane transporter expression. PMID: 23303189
  2. in the Japanese population, STCH might be a new candidate for conferring susceptibility to gastric cancer PMID: 16087163
  3. These results suggest that STCH has a role in cell survival via modulation of the TRAIL-mediated cell death pathway. PMID: 18793616
  4. An entirely novel path is revealed toward therapeutic intervention of tauopathies by inhibition of the previously untargeted ATPase activity of Hsp70. PMID: 19793966
Subcellular Location
Microsome. Endoplasmic reticulum.
Protein Families
Heat shock protein 70 family
Tissue Specificity
Constitutively expressed in all tissues.
Database Links

HGNC: 11375

OMIM: 601100

KEGG: hsa:6782

STRING: 9606.ENSP00000285667

UniGene: Hs.352341

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