Code | CSB-YP013096HU |
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Size | $250 |
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The recombinant Human LRP2 was expressed with the amino acid range of 1186-1389. This LRP2 protein is theoretically predicted to have a molecular weight of 24.2 kDa. This LRP2 recombinant protein is manufactured in yeast. The LRP2 gene fragment has been modified by fusing the N-terminal 6xHis tag, providing convenience in detecting and purifying the recombinant LRP2 protein during the following stages.
The human low-density lipoprotein receptor-related protein 2 (LRP2) is a large endocytic receptor involved in the internalization of various ligands. LRP2 is primarily expressed in tissues with absorptive and endocytic functions, including the kidney, lung, and intestine. LRP2 plays a key role in the reabsorption of proteins, nutrients, and other ligands in the renal proximal tubules. It functions in conjunction with various ligands, including lipoproteins, vitamins, hormones, and enzymes, facilitating their uptake and transport across cell membranes. Beyond its role in endocytosis, LRP2 is implicated in embryonic development, neurodevelopment, and the maintenance of tissue homeostasis. Dysregulation of LRP2 has been associated with several diseases, including renal disorders and neurodevelopmental conditions. Research on LRP2 encompasses its molecular mechanisms, ligand interactions, and its implications for health and disease.There are currently no reviews for this product.