Recombinant Human Putative uncharacterized protein C11orf80 (C11orf80)

Code CSB-YP847649HU
MSDS
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Source Yeast
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Code CSB-EP847649HU
MSDS
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Source E.coli
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Code CSB-EP847649HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP847649HU
MSDS
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Source Baculovirus
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Code CSB-MP847649HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
TOP6BL
Uniprot No.
Alternative Names
C11orf80; Chromosome 11 open reading frame 80; CK080_HUMAN; Putative uncharacterized protein C11orf80; Uncharacterized protein C11orf80
Species
Homo sapiens (Human)
Expression Region
24-677
Target Protein Sequence
EEGAAAA AAAAGGYPST GRCRCSLRGM EGTAVAVFEI LRFLIIHWKC DIDVSKGALL EGQLVISIEG LNSKHQANAL HCVTTRWSLT LLPRPECSGA VSAHCNLHLP GSSDSHASVP RVAGITDAHH HAWLIMVASA GSLFGGMVLK KFLKEIQSIL PGISAKLTWT SEEGSYSQDM TGVTPFQMIF EVDEKPRTLM TDCLVIKHFL RKIIMVHPKV RFHFSVKVNG ILSTEIFGVE NEPTLNLGNG IALLVDSQHY VRPNFGTIES HCSRIHPVLG HPVMLFIPED VAGMDLLGEL ILTPAAALCP SPKVSSNQLN RISSVSIFLY GPLGLPLILS TWEQPMTTFF KDTSSLVDWK KYHLCMIPNL DLNLDRDLVL PDVSYQVESS EEDQSQTMDP QGQTLLLFLF VDFHSAFPVQ QMEIWGVYTL LTTHLNAILV ESHSVVQGSI QFTVDKVLEQ HHQAAKAQQK LQASLSVAVN SIMSILTGST RSSFRKMCLQ TLQAADTQEF RTKLHKVFRE ITQHQFLHHC SCEVKQQLTL EKKDSAQGTE DAPDNSSLEL LADTSGQAEN KRLKRGSPRI EEMRALRSAR APSPSEAAPR RPEATAAPLT PRGREHREAH GRALAPGRAS LGSRLEDVLW LQEVSNLSEW LSPSPGP
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
Gene References into Functions
  1. Top association findings suggested that the bipolar disorder risk allele at SNP rs10896235 in C11orf80 may be associated with increased risk of headache, including migraine. PMID: 27529678
Subcellular Location
Chromosome.
Protein Families
TOP6B-like family
Tissue Specificity
Detected in lung, spleen,colon and in skeletal muscle. Expressed in the ovaries, Fallopian tubes and uterus.
Database Links

HGNC: 26197

OMIM: 616109

KEGG: hsa:79703

UniGene: Hs.292088

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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