Recombinant Human Serine protease 57 (PRSS57)

Code CSB-YP757789HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP757789HU
MSDS
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Source E.coli
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Code CSB-EP757789HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP757789HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP757789HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
PRSS57
Uniprot No.
Alternative Names
PRSS57; PRSSL1; UNQ782/PRO1599Serine protease 57; EC 3.4.21.-; Neutrophil serine protease 4; NSP4; Serine protease 1-like protein 1
Species
Homo sapiens (Human)
Expression Region
32-283
Target Protein Sequence
AQIIGGHEV TPHSRPYMAS VRFGGQHHCG GFLLRARWVV SAAHCFSHRD LRTGLVVLGA HVLSTAEPTQ QVFGIDALTT HPDYHPMTHA NDICLLRLNG SAVLGPAVGL LRPPGRRARP PTAGTRCRVA GWGFVSDFEE LPPGLMEAKV RVLDPDVCNS SWKGHLTLTM LCTRSGDSHR RGFCSADSGG PLVCRNRAHG LVSFSGLWCG DPKTPDVYTQ VSAFVAWIWD VVRRSSPQPG PLPGTTRPPG EAA
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Serine protease that cleaves preferentially after Arg residues. Can also cleave after citrulline (deimidated arginine) and methylarginine residues.
Gene References into Functions
  1. Structural insights in to substrate recognition by the trypsin-fold protease NSP4. PMID: 25156428
  2. cathepsin C was identified as the activator of NSP4 in vivo, as cathepsin C deficiency resulted in a complete absence of NSP4 in a Papillon-Lefevre patient PMID: 23904161
Subcellular Location
Cytoplasmic granule lumen. Secreted.
Protein Families
Peptidase S1 family
Tissue Specificity
Detected in peripheral blood neutrophil granulocytes, but not in other types of leukocytes. Detected in neutrophils and neutrophil precursors in bone marrow (at protein level). Detected in myeloblasts and promyelocytes in bone marrow.
Database Links

HGNC: 31397

KEGG: hsa:400668

STRING: 9606.ENSP00000327386

UniGene: Hs.245146

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