Recombinant Mouse 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (Acmsd)

Code CSB-YP848136MO
MSDS
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Source Yeast
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Code CSB-EP848136MO
MSDS
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Source E.coli
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Code CSB-EP848136MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP848136MO
MSDS
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Source Baculovirus
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Code CSB-MP848136MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Acmsd
Uniprot No.
Alternative Names
Acmsd2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; EC 4.1.1.45; Picolinate carboxylase
Species
Mus musculus (Mouse)
Expression Region
1-336
Target Protein Sequence
MKIDIHTHIL PKEWPDLEKR FGYGGWVQLQ QQGKGEAKMI KDGKLFRVIQ QNCWDPEVRI REMNQKGVTV QALSTVPVMF SYWAKPKDTL ELCQFLNNDL AATVARYPRR FVGLGTLPMQ APELAVEEME RCVKALGFPG IQIGSHINTW DLNDPELFPI YAAAERLNCS LFVHPWDMQM DGRMAKYWLP WLVGMPSETT MAICSMIMGG VFEKFPKLKV CFAHGGGAFP FTIGRIAHGF NMRPDLCAQD NPSDPRKYLG SFYTDSLVHD PLSLKLLTDV IGKDKVMLGT DYPFPLGEQE PGKLIESMAE FDEETKDKLT AGNALAFLGL ERKLFE
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
Gene References into Functions
  1. Acmsd gene expression was found to be under the control of both hepatocyte nuclear factor 4alpha (HNF4alpha) and peroxisome proliferator-activated receptor alpha (PPARalpha). PMID: 16807375
Protein Families
Metallo-dependent hydrolases superfamily, ACMSD family
Tissue Specificity
Highest expression in kidney with lower levels in liver and brain.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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