Recombinant Mouse Activating signal cointegrator 1 complex subunit 1 (Ascc1)

Code CSB-YP002196MO
MSDS
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Source Yeast
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Code CSB-EP002196MO
MSDS
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Source E.coli
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Code CSB-EP002196MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP002196MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP002196MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Ascc1
Uniprot No.
Alternative Names
Ascc1Activating signal cointegrator 1 complex subunit 1; ASC-1 complex subunit p50; Trip4 complex subunit p50
Species
Mus musculus (Mouse)
Expression Region
1-356
Target Protein Sequence
MDVLRPQIVT FDGRNYRKNP IQEKQYQHEE DEDFYPDSME YSDEPCGAYE VAQTPHGFRA TVSAPSLLYK HIVGKRGDTK KKIEVETKTS INIPKHGHEG EIVITGQHRN GVVSARTRID VLLDTFRRRQ PFTHFLSFFL NEVEVQERFL MFQEEVLRKC SKDRGVDSTI FQNPKKLHLT IGMLVLLSEQ EIQQTCEILQ RCKEEFINDI SGGRPLEVEM AGIEYMNDDP AMVDVLYAKV HMKDGSNRLQ ELVDRVLERF QSLGLIVKEW TSVKLHATVM NTLLRKDPNA EGRYNLYTAD GKYIFKERES FDGRNILKTF ENFYFGSLRL NSIHISQRFT VDSFGNYASC GHVDFS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction.
Gene References into Functions
  1. homozygous and compound-heterozygous nonsense and frameshift TRIP4 and ASCC1 mutations that cosegregated with the Prenatal Spinal Muscular Atrophy and Congenital Bone Fracture phenotype PMID: 26924529
Subcellular Location
Nucleus. Nucleus speckle.
Tissue Specificity
Expressed in the spinal cord, brain, paraspinal ganglia, thyroid, and submandibular glands.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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