Recombinant Probable ubiquitin carboxyl-terminal hydrolase 46 (usp-46)

Code CSB-YP341545CXY
MSDS
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Source Yeast
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Code CSB-EP341545CXY
MSDS
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Source E.coli
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Code CSB-EP341545CXY-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP341545CXY
MSDS
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Source Baculovirus
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Code CSB-MP341545CXY
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
usp-46
Uniprot No.
Alternative Names
usp-46; R10E11.3Ubiquitin carboxyl-terminal hydrolase 46; EC 3.4.19.12; Deubiquitinating enzyme; Ubiquitin thioesterase; Ubiquitin-specific-processing protease
Species
Caenorhabditis elegans
Expression Region
2-426
Target Protein Sequence
GATGSSQLE KEISTTESVN NANEHYYGLV NFGNTCYCNS VIQALFFCRP FREKVLNYKQ TLKKSGASKD NLVTCLADLF HSIASQKRRV GTIAPKRFIT KLKKENELFD NYMQQDAHEF FNYLINTISE TLIQEKIAER EKASRHGTLK KGNVTVNLAP ATAGLPRSDE KGTSERNGGI TVEGNEFLNK SDTTTWIHEI FQGILTNETR CLSCETVSSK DEDFLDLSID VEQNTSISHC LRVFSETETL CGDQKYFCET CSSKQEAQKR MRIKKPPQLL ALHLKRFKFV EPLNRHTKLS YRVVFPLELR LFNVSDDAEY GDRMYDLVAT VVHCGATPNR GHYITLVKSN SFWLVFDDDI VEKLEVSSME EFSGMSTDAN IQMPPGNQSA PQKNSESAYI LFYQARDYAA DDPNHNHKGK NSTHSV
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Regulates the abundance of the glr-1 glutamate receptor in the ventral nerve cord by promoting its deubiquitination and preventing its degradation in the lysosome. Contributes to the regulation of embryonic polarity.
Gene References into Functions
  1. The deubiquitinating enzyme ubiquitin-specific protease-46 (USP-46) regulates the abundance of the glutamate receptor GLR-1 in the ventral nerve cord of Caenorhabditis elegans. PMID: 21273419
Subcellular Location
Perikaryon. Cytoplasm. Note=In ventral nerve cord interneurons, localized to discrete puncta within the perikaryon. In the ventral nerve cord, localized diffusely throughout the cytoplasm and to punctate structures.
Protein Families
Peptidase C19 family
Tissue Specificity
Expressed in a number of tissues including the nervous system, pharynx, body wall muscle, vulva muscle and intestine and is detected in many head and ventral cord neurons.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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