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Recombinant Varicella-zoster virus Transcriptional transactivator IE62 (ORF62), partial

Recombinant Varicella-zoster virus Transcriptional transactivator IE62 (ORF62), partial

Code	CSB-YP362655VAP
MSDS	MSDS
Size	Pls inquire
Source	Yeast
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Code	CSB-EP362655VAP
MSDS	MSDS
Size	Pls inquire
Source	E.coli
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Code	CSB-EP362655VAP-B
MSDS	MSDS
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP362655VAP
MSDS	MSDS
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP362655VAP
MSDS	MSDS
Size	Pls inquire
Source	Mammalian cell
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ORF62;

Uniprot No.

P09310

Alternative Names

ORF62;; ORF71; Major viral transcription factor ICP4 homolog; Immediate-early protein 62; IE62

Species

Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Transcriptional transactivator. May interact with and recruit specific components of the general transcription machinery to viral promoters and stabilize their formation for transcription initiation. Negatively regulates its own transcription. This immediate early (EI) protein may be necessary in virion for viral pathogenesis.

Gene References into Functions

ORF62 exhibited highest frequency of mutations during culture conditions in vitro. PMID: 29242077
Sp cellular transcription factors have differential effects on viral promoter activation by varicella-zoster virus IE62 protein. PMID: 26207799
IE62 is a substrate for CDK1/cyclin B1, and virions could deliver the active cellular kinase to nondividing cells that normally do not express it PMID: 18799590

Subcellular Location

Host nucleus. Host cytoplasm. Virion tegument.

Protein Families

Herpesviridae ICP4 family

Database Links

KEGG: vg:1487695

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