Recombinant Human ER lumen protein retaining receptor 1(KDELR1)

Code CSB-CF012129HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P24390
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names KDELR1
Protein Names Recommended name: ER lumen protein retaining receptor 1 Alternative name(s): KDEL endoplasmic reticulum protein retention receptor 1 Short name= KDEL receptor 1 Putative MAPK-activating protein PM23
Expression Region 1-212
Tag Info N-terminal 10xHis-tagged
Protein Description Full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi.
Subcellular Location Cytoplasmic vesicle, COPI-coated vesicle membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane, Multi-pass membrane protein, Endoplasmic reticulum-Golgi intermediate compartment membrane
Protein Families ERD2 family
Database Links

HGNC: 6304

OMIM: 131235

KEGG: hsa:10945

STRING: 9606.ENSP00000329471

UniGene: Hs.515515

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