Recombinant Human Uncharacterized protein C11orf92 (C11orf92)

Code CSB-CF751177HU
MSDS
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
COLCA1
Uniprot No.
Alternative Names
COLCA1; C11orf92; Colorectal cancer-associated protein 1
Species
Homo sapiens (Human)
Expression Region
1-124
Target Protein Sequence
MESCSVAQAGVLTSPFMWRWTGMAGALSALDNTIEDDADDQLPCGEGRPGWVRGELLGSQ GVCKDSKDLFVPTSSSLYGCFCVGLVSGMAISVLLLASDFRKLDFSRPEPCFEKEASLWF VAQH
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. We found PLCE1, C11orf92-C11orf93, and NOC3L associated with colorectal cancer susceptibility PMID: 24146276
  2. Data implicate COLCA1 and COLCA2 in the pathogenesis of colon cancer. PMID: 24154973
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20530476
  4. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20638935
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20648012
  6. Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator) PMID: 20501757
  7. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 19843678
  8. Observational study of gene-disease association. (HuGE Navigator) PMID: 18753146

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Subcellular Location
Membrane; Single-pass membrane protein. Note=Co-localizes with crystalloid granules of eosinophils and granular organelles of mast cells, neutrophils, macrophages and dendritic cells.
Tissue Specificity
Expressed in gastrointestinal and immune tissue, as well as prostate, testis and ovary. Expressed in lamina propria and eosinophils but not in epithelial cells. Expression is greater in benign adjacent tissues than in colon tumors.
Database Links

HGNC: 33789

OMIM: 615693

KEGG: hsa:399948

STRING: 9606.ENSP00000347601

UniGene: Hs.729225

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