Recombinant Mouse Membrane-spanning 4-domains subfamily A member 3(Ms4a3)

Code CSB-CF852830MO
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names Ms4a3
Uniprot No. Q920C4
Alternative Names Ms4a3; Htm4; Membrane-spanning 4-domains subfamily A member 3; Hematopoietic-specific transmembrane protein 4; HTm4
Species Mus musculus (Mouse)
Expression Region 1-213
Protein Length full length protein
Tag Info The following tags are available.
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).
Gene References into Functions
  1. These results suggest that cell surface expression of MS4A3 is useful to distinguish granulocyte/macrophage lineage-committed progenitors from other lineage-related ones in early human hematopoiesis. In conclusion, MS4A3 is useful to monitor early stage of myeloid differentiation in human hematopoiesis. PMID: 29274779
  2. Murine HTm4 is predominantly a hematopoietic protein and highly expressed in the developing and adult murine nervous system. PMID: 15704002
Subcellular Location Membrane; Multi-pass membrane protein.
Protein Families MS4A family
Tissue Specificity Expressed at low levels only in specific immune tissues, such as, spleen, bone marrow and peripheral blood leukocytes.
Database Links

KEGG: mmu:170813

STRING: 10090.ENSMUSP00000108608

UniGene: Mm.240438

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