Recombinant Rabbit Potassium voltage-gated channel subfamily A member 2(KCNA2)

Code CSB-CF600966RB
Size Pls inquire other sizes
Source in vitro E.coli expression system

Product Details

Target Names KCNA2
Uniprot No. Q09081
Species Oryctolagus cuniculus (Rabbit)
Expression Region 1-273
Target Protein Sequence NRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEMFREDEGYIKEEERPL PENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETLPIFRDENDMHGTFHT YSNSTIGYQQTSFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIISIIP YLATLITELVQEDGAQRQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRE LGLLIFFLFIGVILFSSAVYFAEVDEPDSQFPS
Protein Length full length protein
Tag Info The following tags are available.
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.
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Target Data

Function Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane
Subcellular Location Cell membrane, Multi-pass membrane protein, Membrane, Cell projection, axon, Cell junction, synapse, Cell junction, synapse, presynaptic cell membrane, Cell junction, synapse, synaptosome, Endoplasmic reticulum membrane, Cell projection, dendrite, Cell projection, lamellipodium membrane, Cell junction, paranodal septate junction
Protein Families Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.2/KCNA2 sub-subfamily
Tissue Specificity Detected in portal vein myocytes (at protein level) (PubMed:11717160). Detected in portal vein (PubMed:11717160). Brain, liver and kidney.
Database Links

KEGG: ocu:100009479

STRING: 9986.ENSOCUP00000007687

UniGene: Ocu.2363

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