SOX13 Antibody

Code CSB-PA022421GA01HU
Size 100μl
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Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Alternative Names
ICA 12 antibody; ICA12 antibody; Islet cell antibody 12 antibody; Islet cell antigen 12 antibody; MGC117216 antibody; SOX 13 antibody; SOX 13 protein antibody; sox13 antibody; SOX13 protein antibody; SOX13_HUMAN antibody; SRY (Sex determining region Y)-box 13 antibody; SRY box 13 antibody; SRY box containing gene 13 antibody; SRY related HMG box gene 13 antibody; SRY sex determining region Y box 13 antibody; Transcription factor SOX 13 antibody; Transcription factor Sox-13 antibody; Type 1 diabetes autoantigen antibody; Type 1 diabetes autoantigen ICA 12 antibody; Type 1 diabetes autoantigen ICA12 antibody
Abbreviation
SOX13
Uniprot No.
Species
Homo sapiens (Human)
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.

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Target Background

Function
(From Uniprot)
Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'. Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube. Binds to the gene promoter of MBP and acts as a transcriptional repressor. Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells. Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells. Promotes brown adipocyte differentiation. Inhibitor of WNT signaling.
Gene References into Functions
  1. the interaction between Hhex and SOX13 may contribute to control Wnt/TCF1 signaling in the early embryo. PMID: 20028982
Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Expressed in exocrine cells and islets of Langerhans in the pancreas (at protein level). Expressed in the pancreas, placenta, kidney, brain, heart, lung, and liver. Expressed in adipose tissue, cervix, colon, esophagus, ovary, prostate, small intestine, s
Database Links

HGNC: 11192

OMIM: 604748

KEGG: hsa:9580

STRING: 9606.ENSP00000356172

UniGene: Hs.201671

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