Code | CSB-E07302m |
Size | 96T,5×96T,10×96T |
Price | Request a Quote or Start an on-line Chat |
Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
The product CSB-E07302m is a sandwich ELISA kit developed to measure levels of mouse angiopoietin 1 (ANG-1) in multiple samples, including serum, plasma, or tissue homogenates. The enzyme-substrate chromogenic reaction is also used to amplify the signal and quantify the levels of the analyte through the intensity of the colored product. The color intensity positively correlates with the amount of ANG-1 bound in the initial step.
ANG-1, encoded by the gene ANGPT1, is an oligomeric-secreted glycoprotein that exerts powerful vascular protective effects by inhibiting plasma leakage and vascular inflammation, as well as preventing endothelial death. It is required for the correct organization and maturation of newly formed vessels and promotes quiescence and structural integrity of adult vasculature. Apart from promoting vessel stability, ANG-1 also stimulates vessel remodeling and angiogenesis and has been implicated in pulmonary hypertension (PH). ANG-1 binds and signals through the receptor tyrosine kinase Tie2.
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