PTGFRN Antibody

Code CSB-PA006299
Size US$100
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  • Western Blot analysis of 293 cells using CD315 Polyclonal Antibody
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
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Product Details

Uniprot No.
Target Names
PTGFRN
Alternative Names
CD315 antibody; CD9 partner 1 antibody; CD9P-1 antibody; CD9P1 antibody; EWI F antibody; EWI-F antibody; FLJ11001 antibody; FPRP antibody; FPRP_HUMAN antibody; Glu Trp Ile EWI motif containing protein F antibody; Glu-Trp-Ile EWI motif-containing protein F antibody; KIAA1436 antibody; Prostaglandin F2 alpha receptor associated protein antibody; Prostaglandin F2 alpha receptor regulatory protein antibody; Prostaglandin F2 receptor inhibitor antibody; Prostaglandin F2 receptor negative regulator antibody; Prostaglandin F2-alpha receptor regulatory protein antibody; Prostaglandin F2-alpha receptor-associated protein antibody; Ptgfrn antibody; SMAP 6 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human CD315.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur. In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration.
Gene References into Functions
  1. These findings show for the first time that CD9P-1 expression positively correlates with the metastatic status of human lung tumor PMID: 21206492
  2. EWI proteins EWI-2 and EWI-F, alpha3beta1 and alpha6beta4 integrins, and protein palmitoylation have contrasting effects on cell surface CD9 organization PMID: 16537545
  3. EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins PMID: 16690612
  4. transferrin receptor and CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells PMID: 17407154
  5. CD9P-1 was shown to exhibit more than 40 different N-glycans, essentially composed of complex and high mannose-type structures. PMID: 17960739
  6. Tetraspanins can play a role on CD9P-1 oligomerization status. PMID: 19703604

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Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Database Links

HGNC: 9601

OMIM: 601204

KEGG: hsa:5738

STRING: 9606.ENSP00000376899

UniGene: Hs.418093

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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