Recombinant Human Trefoil factor 2 protein(TFF2) (Active)


In Stock
Code CSB-AP000351HU
Product Type Other
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q03403
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 130mM NaCl ,lyophilized
Alias Spasmolysin, SP
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ng/ml, corresponding to a specific activity of >1.0x105 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Research Area Cell Biology
Source E.coli
Gene Names TFF2
Expression Region 24-129aa
Tag Info Tag-Free
Mol. Weight 12.0 kDa
Protein Description Full Length of Mature Protein
PubMed ID 2303034; 9070946; 10950923; 15489334
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Function Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).
Subcellular Location Secreted
Tissue Specificity Stomach.
Database Links

HGNC: 11756

OMIM: 182590

KEGG: hsa:7032

STRING: 9606.ENSP00000291526

UniGene: Hs.2979

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