ABCA3 Antibody

Datasheet
Code CSB-PA859942ESR1HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q99758
Image
  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA859942ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA859942ESR1HU at dilution of 1:100

Immunogen Recombinant Human ATP-binding cassette sub-family A member 3 protein (43-203AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Relevance Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3), ABCA3, ABC3
Immunogen Species Human
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Research Area Signal Transduction
Target Names ABCA3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
Involvement in disease Pulmonary surfactant metabolism dysfunction 3 (SMDP3)
Subcellular Location Membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCA family
Tissue Specificity Highly expressed in lung, followed by brain, pancreas, skeletal muscle and heart. Weakly expressed in placenta, kidney and liver. Also expressed in medullary thyroid carcinoma cells (MTC) and in C-cell carcinoma.
Database Links

HGNC: 33

OMIM: 601615

KEGG: hsa:21

STRING: 9606.ENSP00000301732

UniGene: Hs.26630

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