DPY30 Antibody

Code CSB-PA861193LA01HU
Size US$166
  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA861193LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA861193LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DPY30 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Dpy-30-like protein antibody; Dpy-30L antibody; DPY30 antibody; DPY30_HUMAN antibody; HDPY-30 antibody; Protein dpy-30 homolog antibody; Saf19 antibody
Raised in
Species Reactivity
Recombinant Human Protein dpy-30 homolog protein (1-99AA)
Immunogen Species
Homo sapiens (Human)

The DPY30 Antibody (Product code: CSB-PA861193LA01HU) is Non-conjugated. For DPY30 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA861193LB01HU DPY30 Antibody, HRP conjugated ELISA
FITC CSB-PA861193LC01HU DPY30 Antibody, FITC conjugated
Biotin CSB-PA861193LD01HU DPY30 Antibody, Biotin conjugated ELISA
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews
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Applications : Immunohistochemistr y staining

Sample type: cells

Review: Immunohistochemistry (IHC) staining was performed for the TMA with 57 pairs of tissues by two professional pathologists. The primary rabbit anti‑DPY30 antibody (dilution 1:100; incubation at 37˚C for 30 min; cat. no. CSB‑PA861193LA01HU) was purchased from Cusabio Technology LLC.

By Anonymous

Target Background

As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
Gene References into Functions
  1. Dpy30 role in cellular reprogramming and its interactions with Set1 complex PMID: 26691508
  2. results indicate that DPY30 has critical roles in the proliferation, migration, and invasion of gastric cancer cells, and suggest DPY30 might be a therapeutic target in gastric cancer PMID: 26147337
  3. Based on our structural data and cross-linking results, we suggest that Dpy30 may regulate H3K4 methylation according to its copy number in COMPASS PMID: 25542209
  4. these results form the basis for understanding how WRAD(DRY-30) differentially regulates SET1 family complexes in vivo. PMID: 25561738
  5. The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells. PMID: 25139354
  6. A deletion mutation and reduced DPY30 expression in a Spastic Paraplegia type 4 Japanese family. PMID: 24690193
  7. DPY30 regulates pathways in cellular senescence through ID protein expression. PMID: 23872946
  8. determination of the minimum motif of Ash2L that is required for DPY30 interaction; a structural model for the Ash2L-DPY30 interaction PMID: 22231628
  9. First report of SPG4 associated with partial deletions of both the SPAST and DPY30 genes. The partial heterozygous deletion of DPY30 could modify the phenotypic expression of SPG4 patients with this pedigree. PMID: 20857310
  10. The DPY-30 C-terminal domain structure, harboring the conserved DPY-30 motif, is composed of two alpha-helices linked by a sharp loop and forms a typical X-type four-helix bundle required for dimer formation. PMID: 19481096
  11. hDPY-30 (dpy-30-like protein) binds ASH2L directly. The evolutionarily conserved hDPY-30, ASH2L, RBBP5 and WDR5 likely constitute a subcomplex that is shared by all human Set1-like HMT complexes. PMID: 17500065

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Subcellular Location
Nucleus. Golgi apparatus, trans-Golgi network.
Protein Families
Dpy-30 family
Database Links

HGNC: 24590

OMIM: 612032

KEGG: hsa:84661

STRING: 9606.ENSP00000295066

UniGene: Hs.531788

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