Recombinant Bovine Matrix Gla protein (MGP)

Code	CSB-YP013789BO
MSDS	MSDS
Size	Pls inquire
Source	Yeast
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Code	CSB-EP013789BO
MSDS	MSDS
Size	Pls inquire
Source	E.coli
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Code	CSB-EP013789BO-B
MSDS	MSDS
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP013789BO
MSDS	MSDS
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP013789BO
MSDS	MSDS
Size	Pls inquire
Source	Mammalian cell
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

MGP

Uniprot No.

P07507

Alternative Names

MGPMatrix Gla protein; MGP) [Cleaved into: Matrix Gla protein long form; Matrix Gla protein short form]

Species

Bos taurus (Bovine)

Expression Region

20-102

Target Protein Sequence

Y ESHESLESYE INPFINRRNA NSFISPQQRW RAKAQERIRE LNKPQYELNR EACDDFKLCE RYAMVYGYNA AYDRYFRQRR GA

Protein Length

Full Length of Mature Protein

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function

Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.

Gene References into Functions

Selective CaSR activation, either by extracellular calcium or AMG 641, increased MGP expression in vivo in the arterial wall and in vitro in bovine vascular smooth muscle cells. PMID: 21161195
the effect of MGP on calcification and osteogenic differentiation is determined by availability of BMP-2 PMID: 14587031
MGP plays a role in endothelial cell function, by increasing transforming growth factor-beta1 activity and stimulating VEGF expression PMID: 15456771
MGP has a novel binding activity for vitronectin PMID: 15982861
Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein. PMID: 19661459

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Subcellular Location

Secreted.

Protein Families

Osteocalcin/matrix Gla protein family

Database Links

KEGG: bta:282660

UniGene: Bt.3595

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