||Homo sapiens (Human)
V(D)J recombination-activating protein 1
Short name= RAG-1
RING finger protein 74
Including the following 2 domains:
E3 ubiquitin-protein ligase RAG1
||The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
||Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
||This protein is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.