Recombinant Mouse DmX-like protein 2 (Dmxl2), partial

Code CSB-YP805937MO
MSDS
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Source Yeast
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Code CSB-EP805937MO
MSDS
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Source E.coli
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Code CSB-EP805937MO-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP805937MO
MSDS
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Source Baculovirus
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Code CSB-MP805937MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Dmxl2
Uniprot No.
Alternative Names
Dmxl2; Kiaa0856DmX-like protein 2; Rabconnectin-3
Species
Mus musculus (Mouse)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles of neuronal and endocrine homeostatic processes. Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes.
Gene References into Functions
  1. Data provide evidence that DMXL2 plays an important role in the inner ear function. PMID: 27657680
  2. Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice. PMID: 25248098
  3. The DMXL2 interactome, was studied. PMID: 22707207
  4. an important role for Rabconnectin-3 and V-ATPase activity in the Notch signaling pathway in mammalian cells. PMID: 20810660
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.
Tissue Specificity
Expressed in the brain and pituitary gland. Detected in the hippocampus, dentate gyrus, hypothalamus, pyriform cortex and the granular and molecular layers of the cerebellum of adult animals. In the hypothalamus, expression is observed in the arcuate nucl
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