Recombinant Mouse NADPH oxidase activator 1 (Noxa1)

Code CSB-YP015963MO
MSDS
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Source Yeast
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Code CSB-EP015963MO
MSDS
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Source E.coli
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Code CSB-EP015963MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP015963MO
MSDS
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Source Baculovirus
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Code CSB-MP015963MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Noxa1
Uniprot No.
Alternative Names
Noxa1NADPH oxidase activator 1
Species
Mus musculus (Mouse)
Expression Region
1-444
Target Protein Sequence
MSSLGDQIRD WHRGVLAVAR EDWDSALCFF SDVREPLARM YFNRGCVHLM AGDPEAALRA FDQAVTKDTC MAVGFLQRGV ANFQLQRFQE AVSDFQLALA QLRDNAVIDY TQLGLNFKLQ AWEVLYNMAS AQCQAGLWTK AANTLVEAIS KWPEGAQDIL DIAMDKVQKQ VPLQLQQVPK GEVFQPPRRY LKHLEPMDFL GKAKVVASVI PDDHNAQPQQ RSQAEHAGHQ PSSSMCKRVL STTGGHTSPG LYDSLLASRR PGPGPSEVSS GSEGAATKDP ESLVTVTVQC HFTVPLKVPR GTGLSSFQTL LAQALLHQTQ TGQLSYKAPG EERSWIPIST EESLQSIWRN VPVGPGGLQL QCQGVWGRPV LYQVVAQYNY RAQRPEDLDF HQGDTVDVLC EVDEAWLEGH RDGCVGIFPK CFVVPAGAYV EAMLVLGPQP GDQN
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.
Gene References into Functions
  1. NoxA1 is the functional homolog of p67phox in vascular smooth muscle cells (VSMC) that regulates redox signaling and VSMC phenotype. PMID: 20083677
Subcellular Location
Cytoplasm. Cell membrane. Note=Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1.
Protein Families
NCF2/NOXA1 family
Tissue Specificity
Widely expressed with a tissue distribution similar to the one of NOX1. Detected in colon, uterus, prostate, small intestine, stomach, lung, thyroid, aorta, inner ear and salivary glands. Expressed in colon, small intestine and aortic smooth muscle cells
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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