Recombinant Mouse NK1 transcription factor-related protein 2 (Nkx1-2)

Code CSB-YP020723MO
MSDS
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Source Yeast
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Code CSB-EP020723MO
MSDS
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Source E.coli
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Code CSB-EP020723MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP020723MO
MSDS
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Source Baculovirus
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Code CSB-MP020723MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Nkx1-2
Uniprot No.
Alternative Names
BB238F13.2; C10orf121; Homeobox protein SAX-1; NK1 homeobox 2; NK1 transcription factor related locus 2; NK1 transcription factor-related protein 2; NKX-1.1; NKX1-2; NKX12_MOUSE; Sax1; Sax1-like; Spinal cord axial homeobox gene 1
Species
Mus musculus (Mouse)
Expression Region
1-305
Target Protein Sequence
MLAWQDVGAK AAPSHHKISF SVLDILDPQK FTRAALPPVR LAALEAKKSL EEVEAGQDAC SGNPIGSQET PDAVGRGIDP GSPVEGSEAE EEEEAEDAGR AHQPERWQGV HEGSPEARAV AVGTEESGAE GLPASPGSPG SPRPRRRRAE SSCAKPRRAR TAFTYEQLVA LENKFRATRY LSVCERLNLA LSLSLTETQV KIWFQNRRTK WKKQNPGADG AVQAGGGAPQ PGTPGAVAGG GGSATGSSPG PPVPGALPYQ TFPTYPATNV LFPAASFPLT TAANGSPFTP FLGPSYLTPF YAPHL
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May function in cell specification, particularly in the CNS.
Gene References into Functions
  1. In this study use a combination of genomics, CRISPR/Cas9 engineering and TF motif analysis to investigate the transcriptional networks guiding development of the MGE and its descendants. Whereas NKX2-1 is required for initiating MGE characteristics in the VZ. PMID: 30217225
  2. These results suggest that Nkx1-2 is a critical component of the gene regulatory network that operates downstream of Wnt/b-catenin signaling to regulate the formation of mesendoderm. PMID: 22475651
  3. In neurokinin 1 receptor knockout retinas no changes were seen: neurokinin 3 receptor mRNA levels as well as substance P and neurokinin 3 receptor immunostainings were similar to wild types. PMID: 16388914
Subcellular Location
Nucleus.
Protein Families
NK-1 homeobox family
Tissue Specificity
Expression detected in adult brain, testis and spleen. In the testis, expressed in the germ cells of the seminiferous epithelium, in elongating spermatids and in spermatozoa. Expressed throughout the brain with highest levels in regions of the cerebral co
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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