Recombinant Mouse Nostrin (Nostrin)

Code CSB-YP761531MO
MSDS
Size Pls inquire
Source Yeast
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP761531MO
MSDS
Size Pls inquire
Source E.coli
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-EP761531MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-BP761531MO
MSDS
Size Pls inquire
Source Baculovirus
Have Questions? Leave a Message or Start an on-line Chat
Code CSB-MP761531MO
MSDS
Size Pls inquire
Source Mammalian cell
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Purity
>85% (SDS-PAGE)
Target Names
Nostrin
Uniprot No.
Alternative Names
Nostrin; Daip2; Nostrin; Disabled homolog 2-interacting protein 2; Dab2-interacting protein 2; Nitric oxide synthase trafficker; eNOS-trafficking inducer
Species
Mus musculus (Mouse)
Expression Region
1-506
Target Protein Sequence
MRDPLTDCSY NKVYKSLKEF AQHGDNFCKQ ITSVLQQRAN LEISYAKGLQ KLAVRLSKAL QSTKKNCLST AWAWASESMK SAADLHQKLG KAIELEAIKP THQVLSMQEK KRKSLDNEVE KTANLVINNW NQQIKAKKKL MMSTKKHEAL FHLVESSKQS LTQKEKQKLL NKLKKSTEKL EKEDESYYQK NMAGYSTRLK WESTLENCYK SMLELEKERI QLLCNNLNQY SQHISLFGQT LTTCHTQIHC AISKVDVEKD IQALMEETAI LSIENKSELL LADYFEEDPK NPMDKERRKS LLKPKLGRLQ RDIEKASRDK EGLERKLKAL ASSSSFSDAK SQKDMETLMD ENSLKLDLLQ ANSYKLSSVL ADLEQRPKPC HPCSTCIFKW KEKEHSHTYV KISRPLLTKR LEKAESKAPA GGQNNPSSSP SGSTVSQASK HLCKALYTFQ ARQDDELNLE KGDIVTVHEK KEEGWWFGSL KGKRGHFPAA YVEELPPKAG NTATQA
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Gene References into Functions
  1. the SH3 domain of NOSTRIN is involved in the NOSTRIN-TRAF6 interaction and is required for NOSTRIN-induced down-regulation of endothelial cell proteins PMID: 28235804
  2. NOSTRIN is crucial for the localization and function of the muscarinic M3 receptor at the plasma membrane in the aorta. PMID: 26169369
  3. mouse NOSTRIN acts as a transcriptional repressor by binding to the cis-element through its bZIP motif. PMID: 24361894
  4. NOSTRIN participates in FGF signal transduction and vascular development. PMID: 22751148
  5. Results reveal an elegant mechanism of eNOS regulation by PECAM-1 through signal transducers and activators of transcription 3-mediated transcriptional control of NOSTRIN. PMID: 21183735
  6. shares 82% identity with human NOSTRIN; functions in a different fashion from NOSTRIN and its function may be concerted with that of disabled 2(disabled 2 interacting protein 2) PMID: 15596140
  7. The disabled 2 interacting protein 2 represses the expression of its own gene, via a feedback mechanism which involves binding to the promoter region. PMID: 16171775

Show More

Hide All

Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Cytoplasm. Nucleus.
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1