Recombinant Mouse Plastin-1 (Pls1)

Code CSB-YP663696MO
MSDS
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Source Yeast
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Code CSB-EP663696MO
MSDS
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Source E.coli
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Code CSB-EP663696MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP663696MO
MSDS
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Source Baculovirus
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Code CSB-MP663696MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Pls1
Uniprot No.
Alternative Names
Pls1; Plastin-1
Species
Mus musculus (Mouse)
Expression Region
1-630
Target Protein Sequence
MENSTTTISR EELEELQEAF NKIDIDNSGY VSDYELQDLF KEASLPLPGY KVREIVEKIL VVADNNKDGK ISFEEFVSLM QELKSKDISK TFRKIINKRE GITAIGGTSS ISSEGTQHSY SEEEKVAFVN WINKALENDA DCSHLLPMNP NDGSLFKSLA DGILLCKMIN LSEPDTIDER AINKKKLTPF TVSENLNLAL NSASAIGCTV VNIGAQDLKE GKPHLVLGLL WQIIKVGLFA DIEISRNEAL IALLKDGEDL EELMKLSPEE LLLRWVNYHL TNAGWRTINN FSQDIKDSKA YFHLLNQIAP KGDRDDGPAV AIDLSGFNEK NDLKRAGFML QEADKLGCRQ FVTPADVVSG NPKLNLAFVA NLFNTYPCLH KPDNNDIDLN LLEGESKEER TFRNWMNSLG VNPYINHLYS DLADALVIFQ LYEMIRVPVN WSQVNKPPYP ALGGNMKKIE NCNYAVELGK NEAKFSLVGI AGQDLNEGNA TLTLALVWQL MRRYTLKVLS DLGEGEKVTD DIIIKWVNQT LKSANKSTSI SSFKDKSIST SLPVLDLIDA IAPNAVRQEM IKREHLTDED KLNNAKYAIS VARKIGARIY ALPDDLVEVK PKMVMTVFAC LMGKGLNRLK
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.
Gene References into Functions
  1. we have identified a role for L-plastin in stabilizing long-lived podosomes and in enabling macrophage motility PMID: 27614263
  2. PLS1 biases actin toward liquid packing, which allows stereocilia to grow to a greater diameter. PMID: 27811163
  3. Results show that plastin 1 is dispensable for the initial formation of stereocilia. PMID: 25124451
  4. This study identified LPL as being key to alveolar macrophage development and essential to an effective antipneumococcal response. PMID: 24595139
  5. Plastin 1 accumulates in the terminal web and interacts with keratin 19, possibly contributing to anchoring the rootlets to the keratin network. PMID: 19321664

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Subcellular Location
Cytoplasm. Cell projection, stereocilium.
Tissue Specificity
In the inner ear, it is expressed in the organ of Corti. Abundant in the utricle (at protein level).
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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