Recombinant Mouse Protogenin (Prtg), partial

Code CSB-YP641918MO
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP641918MO
MSDS
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Source E.coli
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Code CSB-EP641918MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP641918MO
MSDS
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Source Baculovirus
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Code CSB-MP641918MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Prtg
Uniprot No.
Alternative Names
Prtg; Protogenin; Protein Shen-Dan
Species
Mus musculus (Mouse)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
May play a role in anteroposterior axis elongation.
Gene References into Functions
  1. Overexpression of Prtg and Radil activates alpha5beta1-integrins to high-affinity conformational forms. PMID: 23744351
  2. PRTG is regulated by miRNA9, plays an inhibitory action on survival of chondroblasts and articular chondrocytes during chondrogenesis and osteoarthritis pathogenesis. PMID: 24007463
  3. This study showed that Prtg, which is a highly expressed gene in the E10.5 mouse mandible, using a cDNA subtraction method between mandibles at E10.5 and E12.0. PMID: 21108791
  4. these results suggested that expression of PRTG defines a stage between pluripotent epiblasts and committed neural progenitors, and its signaling plays a critical role in suppressing premature neuronal differentiation during early neural development. PMID: 20335479
  5. Protogenin expression is restricted to posterior neural plate and mesoderm, with an anterior limit at the level of the rhombencephalon. PMID: 16881056

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Subcellular Location
Membrane; Single-pass membrane protein.
Protein Families
Immunoglobulin superfamily, DCC family
Tissue Specificity
From mid-gastrulation to early somite stages, restricted to posterior neural plate and mesoderm with an anterior limit at the level of the rhombencephalon. Posterior restriction is progressively lost during somitogenesis. Expression is maintained in the n
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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