Recombinant Mouse Translin-associated protein X (Tsnax)

Code CSB-YP882580MO
MSDS
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Source Yeast
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Code CSB-EP882580MO
MSDS
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Source E.coli
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Code CSB-EP882580MO-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP882580MO
MSDS
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Source Baculovirus
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Code CSB-MP882580MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Tsnax
Uniprot No.
Alternative Names
Tsnax; Trax; Translin-associated protein X; Translin-associated factor X
Species
Mus musculus (Mouse)
Expression Region
1-290
Target Protein Sequence
MNGKEGPGGF RKRKHDTFPH NQRREGKDAS LSSPVMLAFK SFQQELDARH DKYERLVKLS RDITVESKRT IFLLHRITSA PDMEEILTES ESKLDGVRQK ILQVAQELSG EDMHQFHRAV TTGLQEYVEA VSFQHFIKTR SLISMEEINK QLTFTAEDSG KESKTPPAEG QEKQLVTWRL KLTPVDYLLG VADLTGELMR MCINSVGNGD IDTPFEVSQF LRQVYDGFSF IGNTGPYEVS KKLYTLKQSL AKVENACYAL KVRGSEIPKH MLADVFSVKT DMIDQEESIS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis.
Gene References into Functions
  1. TRAX is required for DNA repair, by interacting with activated ATM and protects cells from genotoxic stress-induced apoptosis. PMID: 26096928
  2. The TB-RBP-related and -interacting protein Translin-associated factor X was reduced to 50% normal levels in heterozygotes and was absent in TB-RBP-null animals. PMID: 12944470
  3. TRAX is post-transcriptionally stabilized by TB-RBP and both proteins are needed for normal cell proliferation PMID: 14711818
  4. Trax was found to accumulate in the Golgi complex of mid-late pachytene spermatocytes PMID: 15314092
Subcellular Location
Cytoplasm, perinuclear region. Golgi apparatus. Nucleus.
Protein Families
Translin family
Tissue Specificity
Detected in heart, brain, lung, liver, kidney and testis.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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