Recombinant Mouse Zinc finger protein 467 (Znf467)

Code CSB-YP026770MO
MSDS
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Source Yeast
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Code CSB-EP026770MO
MSDS
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Source E.coli
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Code CSB-EP026770MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP026770MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP026770MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Znf467
Uniprot No.
Alternative Names
Znf467; Ezi; Zfp467; MNCb-3350Zinc finger protein 467; Endothelial cell-derived zinc finger protein; EZI
Species
Mus musculus (Mouse)
Expression Region
1-594
Target Protein Sequence
MRETLEALNS LGFSVGQPEM APQSEPRDGF SNAQEKMSSR GESTLHSCSG HETPGQKEGI HTEQAEAPCM GSQASTPQKA EPAGSVPGEE WMIRKVKVED EDQEAEEEVE WPQHLSFLPS PFPTPDLGQL AVTYKLEPGT PGALGGIALS GWAPIPEKPY GCEECERRFR DQLTLRLHQR LHRGEGPCAC PDCGRSFTQR AHMLLHQRSH RGERPFPCSE CDKRFSKKAH LTRHLRTHTG ERPYPCAECG KRFSQKIHLG SHQKTHTGER PFPCTECEKR FRKKTHLIRH QRIHTGERPY QCTQCTRSFT HKQHLVRHQR VHDAASRTRS SPDIPVAPHS PTASLTPSPP GPKPFACSHC GQSFGWKKNL ATHQSLHLTE GRPFGCDECA LGTNVDPAAE PSACTPHAPD CGPGSGPAAP QRTTSSERSF FCPDCGRGFA HGQHLARHRR VHTGERPFAC AQCGRRFGSR PNLVAHSRAH SGARPFACAQ CGRRFSRKSH LGRHQAVHTG SRPHACAVCA RCFSSKTNLV RHQAIHTGSR PFSCPQCAKS FSRKTHLVRH QRIHGDAALP APASNLSAPA WSNPSEVVPP PIFF
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of stromal cells. Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE). Transactivates several promoters including FOS, OSM and PPARG. Recruits a histone deacetylase complex.
Gene References into Functions
  1. these results indicate that Zfp467 regulates the differentiation of adipose-derived stem cells via a mechanism involving Sost-mediated inhibition of Wnt signaling, suggesting potential therapeutic targets for the treatment of osteoporosis. PMID: 25490389
  2. Zfp467 play an important role in adipose derived stem cells differentiation to adipocyte and osteoblast. PMID: 22252242
  3. Zfp467 is a novel co-factor that promotes adipocyte differentiation and suppresses osteoblast differentiation PMID: 21123171
  4. EZI. EZI is a novel nuclear zinc finger protein that augments STAT3 activity by keeping it in the nucleus. PMID: 12426389
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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