Recombinant Pig Apolipoprotein A-IV (APOA4)

Code CSB-YP001916PI
MSDS
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Source Yeast
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Code CSB-EP001916PI
MSDS
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Source E.coli
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Code CSB-EP001916PI-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP001916PI
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP001916PI
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
APOA4
Uniprot No.
Alternative Names
APOA4Apolipoprotein A-IV; Apo-AIV; ApoA-IV; Apolipoprotein A4
Species
Sus scrofa (Pig)
Expression Region
21-382
Target Protein Sequence
EVNADQVATV MWDYFSQLGS NAKKAVEHLQ KSELTQQLNT LFQDKLGEVN TYTEDLQKKL VPFATELHER LTKDSEKLKE EIRRELEELR ARLLPHATEV SQKIGDNVRE LQQRLGPFTG GLRTQVNTQV QQLQRQLKPY AERMESVLRQ NIRNLEASVA PYADEFKAKI DQNVEELKGS LTPYAEELKA KIDQNVEELR RSLAPYAQDV QEKLNHQLEG LAFQMKKQAE ELKAKISANA DELRQKLVPV AENVHGHLKG NTEGLQKSLL ELRSHLDQQV EEFRLKVEPY GETFNKALVQ QVEDLRQKLG PLAGDVEGHL SFLEKDLRDK VNTFFSTLKE EASQGQSQAL PAQEKAQAPL EG
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Gene References into Functions
  1. MTTP is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption. PMID: 21127258
  2. down-regulation of apolipoprotein A-I and A-IV messages in the liver may be mediated by interleukin 6 and tumor necrosis factor-alpha PMID: 15878672
  3. Hepatocyte nuclear factor 4 alpha (HNF-4 alpha)induces apoliprotein IV gene in response to dietary lipids in the intestine. PMID: 17556588
  4. APOA4 genes with SNPs PMID: 18777092
Subcellular Location
Secreted.
Protein Families
Apolipoprotein A1/A4/E family
Tissue Specificity
Secreted in plasma.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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