Recombinant Rat Aflatoxin B1 aldehyde reductase member 3 (Akr7a3)

Code CSB-YP001551RA
MSDS
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Source Yeast
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Code CSB-EP001551RA
MSDS
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Source E.coli
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Code CSB-EP001551RA-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP001551RA
MSDS
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Source Baculovirus
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Code CSB-MP001551RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Akr7a3
Uniprot No.
Alternative Names
Akr7a3; Afar; Akr7a1Aflatoxin B1 aldehyde reductase member 3; AFB1-AR; EC 1.-.-.-; Aflatoxin B1 aldehyde reductase member 1; rAFAR1
Species
Rattus norvegicus (Rat)
Expression Region
1-327
Target Protein Sequence
MSQARPATVL GAMEMGRRMD VTSSSASVRA FLQRGHTEID TAFVYANGQS ETILGDLGLG LGRSGCKVKI ATKAAPMFGK TLKPADVRFQ LETSLKRLQC PRVDLFYLHF PDHGTPIEET LQACHQLHQE GKFVELGLSN YVSWEVAEIC TLCKKNGWIM PTVYQGMYNA ITRQVETELF PCLRHFGLRF YAFNPLAGGL LTGRYKYQDK DGKNPESRFF GNPFSQLYMD RYWKEEHFNG IALVEKALKT TYGPTAPSMI SAAVRWMYHH SQLKGTQGDA VILGMSSLEQ LEQNLALVEE GPLEPAVVDA FDQAWNLVAH ECPNYFR
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. Probably involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Gene References into Functions
  1. Results demonstrate that Akr7a3 mRNA and protein levels are consistently co-expressed along with Akr1b10, in both experimental rat liver carcinogenesis and some human hepatocellular carcinoma samples. PMID: 29383608
  2. A dimeric member of the aldo-keto reductase superfamily; structure resolved to 1.38A resolution (AKR7A1, aflatoxin dialdehyde reductase AKR7A1) PMID: 11839745
  3. structure and chromosomal localization and idetification of antioxidant response elements in the gene promoter PMID: 12727802
Subcellular Location
Cytoplasm.
Protein Families
Aldo/keto reductase family, Aldo/keto reductase 2 subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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