Recombinant Rat Aldehyde dehydrogenase, dimeric NADP-preferring (Aldh3a1)

Code CSB-YP001572RA
MSDS
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Source Yeast
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Code CSB-EP001572RA
MSDS
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Source E.coli
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Code CSB-EP001572RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP001572RA
MSDS
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Source Baculovirus
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Code CSB-MP001572RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Aldh3a1
Uniprot No.
Alternative Names
Aldh3a1; Aldd; Aldh3Aldehyde dehydrogenase; dimeric NADP-preferring; EC 1.2.1.5; Aldehyde dehydrogenase family 3 member A1; HTC-ALDH; Tumor-associated aldehyde dehydrogenase
Species
Rattus norvegicus (Rat)
Expression Region
2-453
Target Protein Sequence
SSISDTVKR AREAFNSGKT RSLQFRIQQL EALQRMINEN LKSISGALAS DLGKNEWTSY YEEVAHVLEE LDTTIKELPD WAEDEPVAKT RQTQQDDLYI HSEPLGVVLV IGAWNYPFNL TIQPMVGAVA AGNAVILKPS EVSGHMADLL ATLIPQYMDQ NLYLVVKGGV PETTELLKER FDHIMYTGST AVGKIVMAAA AKHLTPVTLE LGGKSPCYVD KDCDLDVACR RIAWGKFMNS GQTCVAPDYI LCDPSIQNQI VEKLKKSLKD FYGEDAKQSR DYGRIINDRH FQRVKGLIDN QKVAHGGTWD QSSRYIAPTI LVDVDPQSPV MQEEIFGPVM PIVCVRSLEE AIQFINQREK PLALYVFSNN EKVIKKMIAE TSSGGVTAND VIVHITVPTL PFGGVGNSGM GAYHGKKSFE TFSHRRSCLV KSLLNEEAHK ARYPPSPAKM PRH
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light.
Gene References into Functions
  1. Different doxorubicin formulations decreased liver expression of ALDH3A1. PMID: 26674287
  2. Decreased function of dopamine mediated through DA D(2) receptor in the cerebral cortex and brain stem enhanced the brain, plasma and liver ALDH activity in ethanol treated rats. PMID: 17530188
Subcellular Location
Cytoplasm.
Protein Families
Aldehyde dehydrogenase family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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