Recombinant Rat Interferon-induced guanylate-binding protein 2 (Gbp2)

Code CSB-YP717403RA
MSDS
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Source Yeast
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Code CSB-EP717403RA
MSDS
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Source E.coli
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Code CSB-EP717403RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP717403RA
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP717403RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Gbp2
Uniprot No.
Alternative Names
Gbp2Guanylate-binding protein 1; EC 3.6.5.-; GTP-binding protein 2; GBP-2; Guanine nucleotide-binding protein 2; Interferon-induced guanylate-binding protein 2; p67
Species
Rattus norvegicus (Rat)
Expression Region
1-586
Target Protein Sequence
MASEIHMLQP MCLIENTEAH LVINQEALRI LSAINQPVVV VAIVGLYRTG KSYLMNKLAG KRTGFSLGST VQSHTKGIWM WCVPHPKKAG QTLVLLDTEG LEDVEKGDNQ NDCWIFALAV LLSSTFVYNS MGTINQQAMD QLHYVTELTD LIKSKSSPDQ SGIDDSANFV GFFPTFVWAL RDFSLELEVN GKLVTPDEYL EHSLTLKKGA DKKTKSFNEP RLCIRKFFPK RKCFIFDRPA LRKQLCKLET LGEEELCSEF VEQVAEFTSY IFSYSAVKTL SGGIIVNGPR LKSLVQTYVG AISSGSLPCM ESAVLTLAQI ENSAAVQKAI THYEEQMNQK IQMPTETLQE LLDLHRLIER EAIEIFLKNS FKDVDQKFQT ELGNLLISKR DAFIKKNSDV SSAHCSDLIE DIFGPLEEEV KQGTFSKPGG YFLFLQMRQE LEKKYNQAPG KGLEAEAVLK KYFESKEDIV ETLLKTDQSL TEAAKEIEVE RIKAETAEAA NRELAEKQEK FELMMQQKEE SYQEHVRQLT EKMKEEQKKL IEEQDNIIAL KLREQEKFLR EGYENESKKL LREIENMKRR QSPGKC
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Gene References into Functions
  1. Neuronal cells overexpressing GBP2 exhibited up-regulation of GBP2 in the cerebral cortex following traumatic brain injury. PMID: 28239766
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane; Lipid-anchor.
Protein Families
TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
Tissue Specificity
Widely expressed.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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