Recombinant Rat PEX5-related protein (Pex5l)

Code CSB-YP838789RA
MSDS
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Source Yeast
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Code CSB-EP838789RA
MSDS
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Source E.coli
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Code CSB-EP838789RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP838789RA
MSDS
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Source Baculovirus
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Code CSB-MP838789RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Pex5l
Uniprot No.
Alternative Names
Pex5l; Pex2; Pex5r; Trip8b; PEX5-related protein; PEX5-like protein; Peroxin-5-related protein; TPR-containing Rab8b-interacting protein; Tetratricopeptide repeat-containing Rab8b-interacting protein; Pex5Rp; TRIP8b
Species
Rattus norvegicus (Rat)
Expression Region
1-602
Target Protein Sequence
MYQGHMQGKG SRAADKAVAM VMKEIPREES AEEKPLLTMT SQLVNEQQES RPLLSPSIDD FLCETKSEAI AKPVTSNTAV LTTGLDLLDL SEPVSQTQTK AKKSESSSKS SSLKKKADGS DLISADAEQR AQALRGPETS SLDLDIQTQL EKWDDVKFHG DRTSKGHLMA ERKSCSSRAG SKELLWSSEH RSQPELSTGK SALNSESASE LELVAPAQAR LTKEHRWGSA LLSRNHSLEE EFERAKAAVE SDTEFWDKMQ AEWEEMARRN WISENQEAQN QVTVSASEKG YYFHTENPFK DWPGAFEEGL KRLKEGDLPV TILFMEAAIL QDPGNAEAWQ FLGITQAENE NEQAAIVALQ RCLELQPNNL KALMALAVSY TNTSHQQDAC EALKNWIKQN PKYKYLVKNK KGSPGLTRRM SKSPVDSSVL EGVKDLYLEA AHQNGDMIDP DLQTGLGVLF HLSGEFNRAI DAFNAALTVR PEDYSLWNRL GATLANGDRS EEAVEAYTRA LEIQPGFIRS RYNLGISCIN LGAYREAVSN FLTALSLQRK SRNQQQVPHP AISGNIWAAL RIALSLMDQP ELFQAANLGD LDVLLRAFNL DP
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.
Gene References into Functions
  1. Nedd4-2 plays an important role in the regulation of HCN1 trafficking and may compete with TRIP8b(1a-4) in this process PMID: 24451387
  2. Our data suggest complex regulatory functions of TRIP8b in neuronal endocytosis through independent interaction with membrane proteins and components of the clathrin coat PMID: 21749376
  3. A role of TRIP8b in receptor-mediated endocytosis. PMID: 18620529
  4. although TRIP8b exists in multiple splice isoforms, our data suggest that the predominant role of this protein in brain is to promote h channel surface expression and enhance its current PMID: 19439603
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein. Note=Some fraction is membrane associated via its interaction with RAB8B.
Protein Families
Peroxisomal targeting signal receptor family
Tissue Specificity
Brain specific.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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