Recombinant Rat Solute carrier organic anion transporter family member 1B2 (Slco1b2), partial

Code CSB-YP879483RA
MSDS
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Source Yeast
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Code CSB-EP879483RA
MSDS
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Source E.coli
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Code CSB-EP879483RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP879483RA
MSDS
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Source Baculovirus
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Code CSB-MP879483RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Slco1b2
Uniprot No.
Alternative Names
Slco1b2; Oatp1b2; Slc21a10Solute carrier organic anion transporter family member 1B2; Liver-specific organic anion transporter 1; rLST-1; Sodium-independent organic anion-transporting polypeptide 4; OATP-4; Solute carrier family 21 member 10
Species
Rattus norvegicus (Rat)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Mediates the Na(+)-independent uptake of organic anions such as taurochlate, bromosulfophthalein and steroid conjugates such as estrone-3-sulfate, 17-beta-glucuronosyl estradiol, dehydroepiandrosterone sulfate and prostaglandin E2.
Gene References into Functions
  1. investigation of role of OATP1B3 in drug metabolism/distribution: Data indicate that hepatic uptake of telmisartan mainly consists of a saturable process mediated by OATP1B3. PMID: 21812443
  2. Detailed DNA sequence analysis reveales major functional features of the sequence. PMID: 12180343
  3. Oatp2 and Oatp4 levels were unaffected during obstructive cholestasis. PMID: 17845533
Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein. Note=Confined to the basolateral plasma membrane of hepatocytes.
Protein Families
Organo anion transporter (TC 2.A.60) family
Tissue Specificity
Liver specific. Expression is highest in central perivenous hepatocytes and lowest in the periportal region. Isoform 1 predominates. Not detected in heart, brain, kidney, skeletal muscle, lung, testis or spleen.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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