Recombinant Rabbit Transmembrane protein 109(TMEM109)

Code CSB-CF023678RB
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names TMEM109
Uniprot No. O77751
Alternative Names
TMEM109; Transmembrane protein 109; Mitsugumin-23; Mg23
Species Oryctolagus cuniculus (Rabbit)
Expression Region 34-243
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death. Can form voltage-gated calcium and potassium channels in vitro.
Gene References into Functions
  1. purified MG23 (from skeletal muscle sarcoplasmic reticulum) behaves as a voltage-dependent, cation-conducting channel, permeable to both K+ and Ca2+; data suggest that MG23 forms a large bowl-shaped complex equipped with a putative central pore PMID: 21381722
Subcellular Location Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed. Expressed in skeletal, cardiac and smooth muscle cells, in brain, including neuroglial cells, cerebral cortex neurons and cerebellum, but not Purkinje cells. Also detected in Paneth and Goblet cells of the small intestine (but not in the
Database Links

KEGG: ocu:100008604

STRING: 9986.ENSOCUP00000013488

UniGene: Ocu.2219

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